The outstanding phase‐noise performance of optical frequency combs has led to a revolution in optical synthesis and metrology, covering a myriad of applications, from molecular spectroscopy to laser ranging and optical communications. However, the ideal characteristics of an optical frequency comb are application dependent. In this review, the different techniques for the generation and processing of high‐repetition‐rate (>10 GHz) optical frequency combs with technologies compatible with optical communication equipment are covered. Particular emphasis is put on the benefits and prospects of this technology in the general field of radio‐frequency photonics, including applications in high‐performance microwave photonic filtering, ultra‐broadband coherent communications, and radio‐frequency arbitrary waveform generation.