Potential use of bitter melon (Momordica charantia) derived compounds as antidiabetics: in silico and in vivo studies
Momordica charantia (bitter lemon) belongs to the cucurbitaceae family which has been
extensively used in traditional medicines for the cure of various ailments such as cancer and
diabetes. The underlying mechanism of M. charantia to maintain glycemic control was
investigated. GLP-1 and DPP-4 gene modulation by M. charantia (5–20% inclusion in rats
diet) was investigated in vivo by RT-PCR and possible compounds responsible for diabetic
action predicted through in silico approach. Phytochemicalss previously characterized from …
extensively used in traditional medicines for the cure of various ailments such as cancer and
diabetes. The underlying mechanism of M. charantia to maintain glycemic control was
investigated. GLP-1 and DPP-4 gene modulation by M. charantia (5–20% inclusion in rats
diet) was investigated in vivo by RT-PCR and possible compounds responsible for diabetic
action predicted through in silico approach. Phytochemicalss previously characterized from …
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