[HTML][HTML] Systematic review of controlled clinical trials on the use of ursodeoxycholic acid for the prevention of hepatic veno-occlusive disease in hematopoietic stem …
Hepatic veno-occlusive disease (HVOD) is a serious life-threatening complication of
hematopoietic stem cell transplantation (HSCT). Currently, there is no optimal therapeutic
strategy and preventive measures are ill-defined. Ursodeoxycholic acid (UA) is well-
tolerated oral medication that has been associated with possible benefit as a prophylactic
agent. We sought to summarize and quantify the clinical effects of prophylactic UA in the
context of HSCT. We undertook a systematic review of studies addressing the use of UA as …
hematopoietic stem cell transplantation (HSCT). Currently, there is no optimal therapeutic
strategy and preventive measures are ill-defined. Ursodeoxycholic acid (UA) is well-
tolerated oral medication that has been associated with possible benefit as a prophylactic
agent. We sought to summarize and quantify the clinical effects of prophylactic UA in the
context of HSCT. We undertook a systematic review of studies addressing the use of UA as …
Systematic Review of Controlled Clinical Trials on the Use of Ursodeoxycholic Acid for the Prevention of Hepatic Sinusoidal Obstruction Syndrome in Hematopoietic …
Background: Hepatic sinusoidal obstruction syndrome (HSOS) is a serious life-threatening
complication of hematopoietic stem cell transplantation (HSCT). Currently, there is no
optimal therapeutic strategy and preventive measures are ill-defined. Ursodeoxycholic acid
(UA) is well-tolerated, inexpensive oral medication that has been associated with possible
benefit as a prophylactic agent. We sought to summarize and quantify the clinical effects of
prophylactic ursodeoxycholic acid in the context of HSCT. We undertook a systematic review …
complication of hematopoietic stem cell transplantation (HSCT). Currently, there is no
optimal therapeutic strategy and preventive measures are ill-defined. Ursodeoxycholic acid
(UA) is well-tolerated, inexpensive oral medication that has been associated with possible
benefit as a prophylactic agent. We sought to summarize and quantify the clinical effects of
prophylactic ursodeoxycholic acid in the context of HSCT. We undertook a systematic review …
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