Globally, 80% of wastewater, among which 28% came from industry, returned to the ecosystem without treatment or reuse. The discharge of industrial wastewater poses public health and environmental concerns. The necessity and urgency of industrial wastewater treatment (IWT) will bring great challenges to most countries. This paper conducted the patent analysis combined with text mining to quantitatively analyze 11,840 patents related to IWT in the Derwent Innovations Index database. The results showed that: From 1973 to 2020, the number of patents related to IWT annually was increasing consistently. China ranked first in the number of patent publications. In contrast, the United States and some patent organizations, such as World Intellectual Property Organization, produced fewer patents, while they played more important roles in knowledge transfer. The core technology analysis suggested that method, device, material and related industry were hot topics. From activated sludge treatment technology, industrial wastewater treatment technology had gone through a development process from single technology treatment to combined technologies treatment. In the foreseeable future, research on devices for physical treatment, advanced oxidation processes, automated and energy-saving treatment systems were the promising directions.