KE Remy, M Mazer, DA Striker, AH Ellebedy… - JCI insight, 2020 - ncbi.nlm.nih.gov
… The purpose of this study was to determine whether critically ill COVID-19 patients have an exaggerated proinflammatory cytokinestorm versus an immunosuppressive immunological …
RJ Jose, A Manuel - The Lancet Respiratory Medicine, 2020 - thelancet.com
… [TNF], IL-6, and IL-1β) results in what has been described as a cytokinestorm, leading to an … failure, and eventually death when the high cytokine concentrations are unabated over time.…
RQ Cron - The Lancet Rheumatology, 2021 - thelancet.com
… in improving COVID-19 … IL-6 inhibition in the treatment of COVID-19cytokinestorm syn drome. 7 This single-centre, observational study of patients admitted to hospital with COVID-19, …
… Absent the opportunity to enroll patients in one of these studies, we would consider immunosuppression in patients with COVID-19 who have incipient cytokinestorm. Ideally, treatment …
S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
… between cytokinestorm and severe COVID-19 complications, we propose a cytokine storm-based diagnosis and management workflow for patients with or suspected of COVID-19 (…
K Kuppalli, AL Rasmussen - EBioMedicine, 2020 - thelancet.com
… interpretations of COVID-19-specific effects on inflammatory cytokine production and immune … with cytokinestorms and COVID-19 severity, further data from other cohorts of COVID-19 …
… distress syndrome is the so-called “cytokinestorm,” which is an aberrant response from the … cytokines/chemokines. In this review, we will discuss the role of cytokinestorm in COVID-19 …
… As seen in the influenza pandemic of 1918, it has been suggested that a cytokinestorm of … which target the COVID-19 induced cytokinestorm. As this is not exclusive to COVID-19, we …
G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
… cytokine release in response to viral infection, a condition known as cytokine release syndrome (CRS) or cytokinestorm… to ARDS and MOF in COVID-19, thus endorsing the hypothesis …