Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?

D Panigrahy, MM Gilligan, S Huang, A Gartung… - Cancer and metastasis …, 2020 - Springer
… Severe coronavirus disease (COVID-19) is characterized by pulmonary hyper-inflammation …
cytokine storms”. Controlling the local and systemic inflammatory response in COVID-19

The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19

A Attiq, LJ Yao, S Afzal, MA Khan - International immunopharmacology, 2021 - Elsevier
… pathway for cytokine storm. Given … COVID-19 patients. Hence, this review highlights the
activation, signal transduction and cross-talk of NF-κB with regard to cytokine storm in COVID-19. …

COVID-19: consider cytokine storm syndromes and immunosuppression

P Mehta, DF McAuley, M Brown, E Sanchez… - The lancet, 2020 - thelancet.com
… As of March 12, 2020, coronavirus disease 2019 (COVID-19) … with severe COVID-19 might
have a cytokine storm syndrome. We … Current management of COVID-19 is supportive, and …

COVID-19, mast cells, cytokine storm, psychological stress, and neuroinflammation

D Kempuraj, GP Selvakumar, ME Ahmed… - The …, 2020 - journals.sagepub.com
… Therapeutic options are now limited to COVID-19. The hallmark of COVID-19 pathogenesis
is the cytokine storm with elevated levels of interleukin-6 (IL-6), IL-1β, tumor necrosis factor-…

Interleukin-6 perpetrator of the COVID-19 cytokine storm

J Shekhawat, K Gauba, S Gupta, P Purohit… - Indian Journal of Clinical …, 2021 - Springer
IL-6 is also a robust marker for predicting disease prognosis and deterioration … IL-6 in the
immuno-pathology of COVID-19 has been illustrated. The role of IL-6 as a pleiotropic cytokine

Focus shifts to antibody cocktails for COVID-19 cytokine storm

C Harrison - Nature biotechnology, 2020 - go.gale.com
… excessive cytokine release, often referred to as a 'cytokine storm… the cytokine storm proportional
to the severity of COVID-19. … these pro-inflammatory cytokines, particularly IL-6, generally …

An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis

Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
Cytokine storm is associated with a poor disease prognosis [9], [10]. We monitored … cytokines
in 52 hospitalized patients with COVID-19. We initially compared maximal plasma cytokine

Cytokine storm associated coagulation complications in COVID-19 patients: Pathogenesis and Management

SR Savla, KS Prabhavalkar, LK Bhatt - Expert review of anti …, 2021 - Taylor & Francis
… -2 infection, generation of cytokine storm, the interdependence … using COVID-19, cytokine
storm, and coagulation as keywords. … between the ‘cytokine storm’ and COVID-19 progression. …

COVID-19: more than a cytokine storm

G Riva, V Nasillo, E Tagliafico, T Trenti, P Comoli… - Critical care, 2020 - Springer
… In this view, COVID-19-associated cytokine storm, with elevated plasma levels of IL-6, IL-1, …
but the other “key feature” of COVID-19—the progressive lymphopenia with T cell exhaustion […

Prevention of the cytokine storm in COVID-19

DJM Wright - The Lancet Infectious Diseases, 2021 - thelancet.com
… to be a transient manifestation of a cytokine storm, induced by … for COVID-19 in patients
presenting with a cytokine storm and … in the context of the COVID-19 cytokine storm, to establish if …