… In situ imaging of the BBB impairment in animal disease models. (A) … in those animals that
developed spontaneous seizures (image on the right, black color) but not in control animals (…

… of cerebral endothelial cell biology, the complex interactions of the neurovascular unit make
animal‐based models … BBB dysfunction is a complication of neurodegenerative disease and …

… activity and increases seizure frequency in animals with chronic epilepsy (Seiffert … dysfunction
acutely promotes single seizures, facilitates the development of epilepsy in animal models, …

… disorders is still not fully understood. Here, we examine BBB breakdown in animal models
… We discuss the role of BBB breakdown and dysfunction in neurodegenerative process, …

… of brain damage that can result from blood–brain barrier malfunction both in the developing
and ageing brain. … of blood–brain barrier or inflammation in animal models of neurological …

… brain injury. We present an overview of current knowledge about BBB dysfunction in the
developing brain … Some of the principal animal models mentioned in this review with correlate …

… the blood-brain barrier in a mouse model of Sanfilippo type B (MPS III B) at different stages
of disease. The primary focus was determining BBB competence in brain structures known to …

… in animal models and human patients. Conversely, since some portions of Aβ are eliminated
along the neurovascular unit and across the BBB, disturbing the pathways may result in …

… shown in human and animal studies to be protective against AD and PD. One mechanism
implicated in the pathogenesis of AD and PD is blood-brain barrier (BBB) dysfunction and we …

… dysfunction has a critical role in Alzheimer’s disease (AD). Recent data from brain imaging
studies in humans and animal models suggest that cerebrovascular dysfunction may precede …