… of new associations that have been replicated in multiple studies. … We argue here that
bioinformatics has an important role to … GWAS challenges that will require computational methods. …

… Genome-wide association studies (GWAS) are a powerful tool for investigators to examine
… This chapter highlights the challenges that lie ahead for GWAS in better identifying disease …

… thousands of robust associations between common variants … can be utilized for rare variant
association studies (RVASs). In … associations with rare variants and the various bioinformatic …

… research in the form of genome‐wide association studies ( GWAS s). GWAS s have …
associations. Identifying biologically significant variants by GWAS also presents a challenge. The …

… challenges and opportunities exist in the broad area of biomedical informatics. In the context
of this chapter we define bioinformatics … The key challenges to bioinformatics essentially all …

… By addressing the challenges outlined in this review, bioinformatics will create the tools to
… -wide association studies (GWASs) have been used to assess the statistical associations of …

… in bioinformatics. We … challenges that need to be addressed to make association
analysis-based techniques more applicable for a number of interesting problems in bioinformatics…

… Xu and JA Taylor, “SNPinfo: integrating GWAS and candidate gene information into
functional SNP selection for genetic association studies,” Nucleic Acids Res., vol. 37, no. suppl. …

… mapping in genetic association study, especially to tackle the challenges of studying the
gene–… detecting epistasis in genome-wide association studies and proposed a new evolutionary …

… long and identify seven future challenges. The biggest challenge involves the identification
of … Further bioinformatic post-GWAS follow up analyses leverage the fact that there are only …