Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health

A Parker, S Fonseca, SR Carding - Gut microbes, 2020 - Taylor & Francis
brain health, with a focus on the impact of gut microbes, and the metabolites they generate
from dietary components, on blood-brain barrier … potential on brain health of manipulating the …

The bloodbrain barrier

B Obermeier, A Verma, RM Ransohoff - Handbook of clinical neurology, 2016 - Elsevier
… In both health and disease, the BBB acts as mediator between the periphery and the …
blood–cerebrospinal fluid barrier and include a brief aside about evolutionary aspects of barrier

Healthy aging and the bloodbrain barrier

WA Banks, MJ Reed, AF Logsdon, EM Rhea… - Nature aging, 2021 - nature.com
The bloodbrain barrier (BBB) protects the central nervous system (CNS) from unregulated
exposure to the blood and its contents. The BBB also controls the blood-to-brain and brain-to-…

Regulation of bloodbrain barrier integrity by microglia in health and disease: a therapeutic opportunity

PT Ronaldson, TP Davis - Journal of Cerebral Blood Flow & …, 2020 - journals.sagepub.com
The bloodbrain barrier (BBB) is a critical regulator of CNS homeostasis. It possesses physical
and biochemical characteristics (ie tight junction protein complexes, transporters) that are …

Cell‐specific bloodbrain barrier regulation in health and disease: a focus on hypoxia

S Engelhardt, S Patkar… - British journal of …, 2014 - Wiley Online Library
The bloodbrain barrier ( BBB ) is a complex vascular structure consisting of microvascular
endothelial cells that line the vessel wall, astrocyte end‐feet, pericytes, as well as the basal …

Morphogens and blood-brain barrier function in health and disease

NR Wevers, HE de Vries - Tissue barriers, 2016 - Taylor & Francis
… The microvasculature of the brain forms a protective blood-brain barrier (BBB) that ensures
… essential for optimal brain functioning. The barrier properties of the brain endothelial cells are …

Cells of the bloodbrain barrier: an overview of the neurovascular unit in health and disease

HL McConnell, A Mishra - The Blood-Brain Barrier: Methods and Protocols, 2022 - Springer
bloodbrain barrier (BBB) is formed by endothelial cells of the cerebral vasculature and
prevents extravasation of blood products into the brain to … unit to tightly regulate brain blood flow, …

[HTML][HTML] Sex differences in the bloodbrain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar disorder
(BD) and schizophrenia (SZ) are increasing at alarming rates in our societies. Growing …

An overview of the blood-brain barrier

T Barichello, A Collodel, R Hasbun, R Morales - Blood-Brain Barrier, 2019 - Springer
… In 1921, Stern presented the term “Barrière hématoencéphalique” at the Medical Society
of Geneva and she published this new concept about blood-brain barrier (BBB) in a Swiss …

Alcohol, inflammation, and blood-brain barrier function in health and disease across development

AS Vore, T Deak - International review of neurobiology, 2021 - Elsevier
… alcohol compromises overall brain health remain somewhat elusive. A number of brain
diseases and pathological states are accompanied by perturbations in Blood-Brain Barrier (BBB) …