Inflammatory mediators and modulation of bloodbrain barrier permeability

NJ Abbott - Cellular and molecular neurobiology, 2000 - Springer
… perineurium), the brain endothelium forming the bloodbrain barrier can be modulated by
a … of the brain discussed. 2. Methods for measuring bloodbrain barrier permeability in situ …

Regulation of bloodbrain barrier permeability

WG Mayhan - Microcirculation, 2001 - Taylor & Francis
… of permeability of the bloodbrain barrier. Discussion will focus on factors that influence the
permeability of the bloodbrain barrier … on the integrity of the bloodbrain barrier. It is antici…

[HTML][HTML] Factors influencing the blood-brain barrier permeability

Y Zhao, L Gan, L Ren, Y Lin, C Ma, X Lin - Brain research, 2022 - Elsevier
… junctional proteins, can control the barrier permeability. Regarding the need to exchange …
to alter BBB permeability by mediating the structural components and barrier function, because …

Blood-brain barrier permeability and physical exercise

MA Małkiewicz, A Szarmach, A Sabisz… - Journal of …, 2019 - Springer
… exercise and blood-brain barrier (BBB) permeability is … BBB permeability such as systemic
inflammation, the brain renin-… physical exercise diminishes BBB permeability as it reinforces …

Molecular and cellular permeability control at the bloodbrain barrier

SM Gloor, M Wachtel, MF Bolliger, H Ishihara… - Brain research …, 2001 - Elsevier
The bloodbrain barrier (BBB) is formed by brain capillary endothelial cells. These cells have
at least three properties which distinguish them from their peripheral counterparts: (1) tight …

The gut microbiota influences blood-brain barrier permeability in mice

V Braniste, M Al-Asmakh, C Kowal, F Anuar… - Science translational …, 2014 - science.org
… show increased permeability of the blood-brain barrier. This elevated permeability was also
… germ-free mice reduced blood-brain barrier permeability, possibly through the regulation of …

Astrocyte–endothelial interactions and bloodbrain barrier permeability

NJ Abbott - Journal of anatomy, 2002 - Wiley Online Library
… is up-regulation of astrocyte AQP4 mRNA in areas of the rat brain where the blood brain
barrier is disrupted following focal brain ischaemia or physical injury. In contrast AQP4 knockout …

Development of a computational approach to predict blood-brain barrier permeability

X Liu, M Tu, RS Kelly, C Chen, BJ Smith - Drug metabolism and disposition, 2004 - ASPET
… were to generate a data set of blood-brain barrier (BBB) permeability values for drug-like …
to predict BBB permeability from structure. The BBB permeability, expressed as permeability-…

Bloodbrain barrier permeability to small and large molecules

EM Cornford, S Hyman - Advanced drug delivery reviews, 1999 - Elsevier
The objective of this article is to provide the reader with an update of some of the BBB
research highlights which have occurred in recent times, and to review the impact and …

Factors controlling permeability of the bloodbrain barrier

MMA Almutairi, C Gong, YG Xu, Y Chang… - Cellular and molecular life …, 2016 - Springer
barrier for neurons in the brain, the bloodbrain barrier (BBB) exists between the blood
microcirculation system and the brain … The normal BBB integrity is essential in protecting the brain