[HTML][HTML] Cancer modeling: From mechanistic to data-driven approaches, and from fundamental insights to clinical applications

S Bekisz, L Geris - Journal of Computational Science, 2020 - Elsevier
… about cancer modeling and mathematical oncology. First, the different mathematical modeling
approaches that may be applied to biology and particularly cancer biology are stated. The …

[HTML][HTML] Mathematical modeling of prostate cancer and clinical application

T Phan, SM Crook, AH Bryce, CC Maley, EJ Kostelich… - Applied Sciences, 2020 - mdpi.com
… , especially concerning clinical applications. Our focus is on models of prostate cancer
dynamics … gaps between theoretical work and the clinical application of mathematical models. …

Breast cancer risk models: a comprehensive overview of existing models, validation, and clinical applications

JA Cintolo-Gonzalez, D Braun, AL Blackford… - Breast cancer research …, 2017 - Springer
… of existing breast cancer risk prediction models and outlines the … the models into those that
exclusively predict breast cancer risk … Within these categories, major models are presented in …

Multiscale cancer modeling

TS Deisboeck, Z Wang, P Macklin… - Annual review of …, 2011 - annualreviews.org
… Generally, when developing a multiscale cancer model, particularly if a clinical application
… power of the model while at the same time constraining the size of the model as much as …

Concepts in cancer modeling: A brief history

RM Thomas, T Van Dyke, G Merlino, CP Day - Cancer research, 2016 - AACR
… can be translatable to clinical applications. Finally, we will also discuss how the advances
in cancer genomics and cancer modeling will influence each other going forward. Cancer Res…

[图书][B] Handbook of cancer models with applications

WY Tan - 2008 - books.google.com
… and advanced cancer models and their applications from world experts in cancer modelling.
… Part I consists of 11 chapters giving detailed treatment of an assortment of cancer models

Progress and opportunities to advance clinical cancer therapeutics using tumor dynamic models

R Bruno, D Bottino, DP De Alwis, AT Fojo, J Guedj… - Clinical Cancer …, 2020 - AACR
… shown a growing number of applications and a broader adoption by … modeling is also
being investigated in personalized cancer therapy approaches. These models and applications

Application of breast cancer risk prediction models in clinical practice

SM Domchek, A Eisen, K Calzone, J Stopfer… - Journal of Clinical …, 2003 - ascopubs.org
… of developing breast cancer (using risk assessment models) or as the likelihood of detecting
a BRCA1 or BRCA2 mutation (using prior probability models). Each of the models has …

Computational systems biology in cancer: modeling methods and applications

W Materi, DS Wishart - Gene regulation and systems biology, 2007 - journals.sagepub.com
… our understanding of a variety of cancer-related processes including genetic … -cancer
therapy. Overall it is our hope that this review will provide an improved understanding of modeling

Mathematical modeling of cancer immunotherapy for personalized clinical translation

JD Butner, P Dogra, C Chung, R Pasqualini… - Nature computational …, 2022 - nature.com
… , and instead are moving towards immunotherapy models for clinical applications 50 .
Notable advances are emerging towards modeling-derived design of personalized treatment …