The role of dysregulated immune responses in COVID-19 pathogenesis

S Tahaghoghi-Hajghorbani, P Zafari, E Masoumi… - Virus research, 2020 - Elsevier
… In this section, to better understand the effect of age on COVID-19 manifestations, we discuss
immune changes based on the effects of age or immunosenescence on immune cells and …

Cellular immune responses to covid-19

HF Sewell, RM Agius, M Stewart, D Kendrick - Bmj, 2020 - bmj.com
immunity will deepen our insights into covid-19immune response to SARS-CoV-2 involves
four types or subsets of T cells: T helper cells (CD4) are responsible for cellular immunity and …

Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

Y Jamilloux, T Henry, A Belot, S Viel, M Fauter… - Autoimmunity …, 2020 - Elsevier
… type-I interferon response, and lymphopenia. This review provides an overview of current
knowledge on COVID-19 immunopathology. We discuss the defective type-I IFN response, the …

[HTML][HTML] Mucosal immune response in BNT162b2 COVID-19 vaccine recipients

L Azzi, D Dalla Gasperina, G Veronesi, M Shallak… - …, 2022 - thelancet.com
… Here we assessed the mucosal immune response in healthy individuals who underwent the
mRNA BNT162b2 COVID-19 vaccination by measuring total IgG and IgA antibodies against …

[HTML][HTML] The immune response to SARS-CoV-2 and COVID-19 immunopathology–Current perspectives

JL Boechat, I Chora, A Morais, L Delgado - Pulmonology, 2021 - Elsevier
… biology and host immune response. The rapid clinical course seen in COVID-19 indicates
that … mild disease is probably due to the innate immune response, as, considering that SARS-…

Dysregulation of immune response in patients with coronavirus 2019 (COVID-19) in Wuhan, China

C Qin, L Zhou, Z Hu, S Zhang, S Yang… - Clinical infectious …, 2020 - academic.oup.com
19 [1]. However, little is known about lymphocyte subsets and the immune response of patients
with COVID-19… on dysregulated immune response in patients with COVID-19 that SARS-…

HLA, immune response, and susceptibility to COVID-19

F Tavasolian, M Rashidi, GR Hatam, M Jeddi… - Frontiers in …, 2021 - frontiersin.org
… with COVID-19 incidence since HLA plays such a crucial role in the immune response to …
investigation to incorporate HLA alleles when analyzing COVID-19 outcomes (27, 30, 31). …

Considering how biological sex impacts immune responses and COVID-19 outcomes

EP Scully, J Haverfield, RL Ursin… - Nature Reviews …, 2020 - nature.com
… of immunity and highlight potential sex differences underlying COVID-19 severity. We propose
that sex differences in immunopathogenesis will inform mechanisms of COVID-19, identify …

Early insights into immune responses during COVID-19

AL St John, APS Rathore - The Journal of Immunology, 2020 - journals.aai.org
COVID-19 immunity and immune pathology through building a description of the kinetics of
immune responses … of systemic immune responses for long-term immunity against SARS-CoV…

Heightened innate immune responses in the respiratory tract of COVID-19 patients

Z Zhou, L Ren, L Zhang, J Zhong, Y Xiao, Z Jia, L Guo… - Cell host & …, 2020 - cell.com
… To understand the cytokine profile in BALF from the COVID-19 patients, we assigned DEGs
into … These observations suggested that the exuberant inflammation in COVID-19 could be …