N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
… NLRP3inflammasome in COVID-19, this review describes the possible pathways of NLRP3 inflammasome … , the role of the NLRP3inflammasome in the pathogenesis of COVID-19 and …
… -containing 3 (NLRP3) inflammasome pathway and … COVID-19 and NLRP3 activation and describe an important role in targeting this pathway for the treatment of severe COVID-19…
… However, ASC knockouts significantly decreased the levels of IL-1β (89), pointing to the possibility that even if the NLRP3inflammasome is blocked, other inflammasomes that require …
A Shah - Frontiers in immunology, 2020 - frontiersin.org
… NLRP3inflammasome appears to be a potential drug target in the treatment of coronavirus disease 2019 (COVID-19… This manuscript highlights the importance of NLRP3inflammasome …
… In this review, to delineate the interlink between NLRP3inflammasome activation and underlying conditions of COVID-19 severity, we focused on the mechanisms of NLRP3 mediated …
A Lopez-Reyes, C Martinez-Armenta… - Frontiers in …, 2020 - frontiersin.org
… clinical symptoms in COVID-19, we aimed to suggest the possible role of NLRP3 inflammasome as a link between obesity and the increased risk for a severe COVID-19 outcome. …
N Potere, E Garrad, Y Kanthi, M Di Nisio… - Cardiovascular …, 2023 - academic.oup.com
… COVID-19. We also summarize current efforts to target the NLRP3inflammasome pathway in COVID-19… and the therapeutic potential that inflammasome-targeted strategies may provide …
… In Covid-19, high neutrophil recruitment is correlated with disease severity; thereby colchicine may reduce Covid-19 severity through inhibition of NLRP3inflammasome, neutrophil …
… in patients with moderate-to-severe COVID-19. In this review, we summarize … NLRP3 inflammasome and IL-1β in COVID-19, and discuss clinical trials testing IL-1 inhibition in COVID-19…