[HTML][HTML] Monocyte-driven atypical cytokine storm and aberrant neutrophil activation as key mediators of COVID-19 disease severity

L Vanderbeke, P Van Mol, Y Van Herck… - Nature …, 2021 - nature.com
critical COVID-19 hypercytokinemia from MAS cytokine storm. … more than 3-fold higher in
critical COVID-19 than in MAS, … as one of the most important determinants of critical COVID-19 …

[HTML][HTML] A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome …

A Bektas, SH Schurman, C Franceschi, L Ferrucci - Immunity & Ageing, 2020 - Springer
… ), with a substantial proportion leading to a critical illness (respiratory failure, septic shock, …
The unopposed viral load may be a major determinant of the cytokine storm, although with a …

[HTML][HTML] Can the cytokine adsorber CytoSorb® help to mitigate cytokine storm and reduce mortality in critically ill patients? A propensity score matching analysis

C Scharf, I Schroeder, M Paal, M Winkels… - Annals of intensive …, 2021 - Springer
… Furthermore, there were different causes leading to the cytokine storm in our study population.
A precise evaluation of the cause of the cytokine storm or the applying of the CRS criteria …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
… responses induced by a cytokine storm start locally and … To date, it is unclear what
determinants of the host response to … , a cytokine storm is common in patients with severe-to-critical

Excitotoxicity (immunoexcitotoxicity) as a critical component of the cytokine storm reaction in pulmonary viral infections, including SARS-CoV-2

RL Blaylock - International Journal of Vaccine Theory, Practice, and …, 2021 - mail.ijvtpr.com
cytokines, by themselves, may not be sufficient to cause the pathological damage that we
see in cases of cytokine storm is … cytokines and chemokines is an early event in the cytokine

[HTML][HTML] The mechanistic basis linking cytokine storm to thrombosis in COVID-19

A Wolf, F Khimani, B Yoon, C Gerhart, D Endsley… - Thrombosis …, 2022 - Elsevier
… molecule, PAI-1 is a critical determinant of pathophysiology in thrombosis. For instance, it is
… complications that are often concomitantly seen in critically ill, infected patients, and recent …

[HTML][HTML] Health disparities in COVID-19: addressing the role of social determinants of health in immune system dysfunction to turn the tide

Y Baumer, N Farmer, TA Premeaux… - Frontiers in public …, 2020 - frontiersin.org
… at risk for experiencing a cytokine storm and could this help … role for the development of a
cytokine storm, we would like to … backgrounds are enrolled in these critical COVID-19 related …

[PDF][PDF] Cytokines storm of COVID-19 and multi systemic organ failure: A review

ZNM Albarzanji, TA Mahmood, ER Sarhat… - Sys Rev Pharm, 2020 - academia.edu
… Pathophysiology of Acute Lung Injury and the Acute Respiratory Distress syndromeseminars
in respiratory and critical care medicine/volume 27, number 4. 30. Gattinoni L, Coppola S, …

Interferon lambdas: the next cytokine storm

C Kelly, P Klenerman, E Barnes - Gut, 2011 - gut.bmj.com
… of this in clinical practice, the biology of IFNλ3 as currently understood and how this may
impact on HCV infection, and describes the early studies that assess the role of this cytokine in …

Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex

AC Petrey, F Qeadan, EA Middleton… - Journal of Leucocyte …, 2021 - academic.oup.com
critical need to understand the acute-phase cytokine response in COVID-19. To date,
determinants … Although the typical inflammatory cytokines are expected during cytokine storm from …