… to bioactivity of IL-6 and production of cytokinestorm plays a role in COVID-19 complications affecting the A-CMR across different countries. Clinical data on cytokine levels in COVID-19 …
… Cytokinestorm in patients with severe symptoms is understood to be characterized by enhanced serum levels of many cytokines … of treating cytokinestorm within the critical period (5 to …
A Arcanjo, K Guimarães Pinto, J Logullo… - The Journal of …, 2021 - academic.oup.com
… The cytokinestorm syndrome is most commonly triggered by … the development of the cytokine storm consist of a different … in inducing the cytokinestorm in critically ill patients with COVID-…
AC Puhl, GF Gomes, S Damasceno, EJ Fritch… - ACS …, 2022 - ACS Publications
… Studies have revealed higher levels of cytokinestorm associated with more severe COVID-19 development. (12) In these patients, the inflammatory substances from the cytokinestorm …
SM Keating, JW Heitman, S Wu, X Deng… - Journal of …, 2016 - Am Soc Microbiol
… significant insight into critical events occurring during this time. Cytokines, chemokines, and … infections identified here may be important determinants of the subsequent disease course. …
L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
… early and late cytokine profiles in patients with mild, moderate, and severe/critical COVID-19. The secondary objective was to measure the associations between cytokines and length of …
MB Azaiz, AB Jemaa, W Sellami, C Romdhani… - Immunobiology, 2022 - Elsevier
… response, a “Cytokinestorm,” that involves both pro- and anti-inflammatory cytokines. In the … status as represented by the levels of IL-6/IL-10 in severe to critical COVID-19 patients. 66 …
BK Gajjela, MM Zhou - Drug discovery today, 2022 - Elsevier
… a crucial determinant of virulence, acting to promote the overexpression of proinflammatory … GM-CSF is a cytokine that is critical for healthy pulmonary function and is necessary for the …
… [65] suggest a range of potential drugs for treating COVID-19 cytokinestorm including mast cell stabilizing drugs, tryptase inhibitors, zinc-mediated inhibitors, and tryptase-specific …