… This review enlightened the implications and risk factor of hypercytokinemia/cytokinestorm for COVID-19 patients, with special emphasis on potential therapeutic strategies used to …
Ö Karcıoğlu, G Afacan, B Özkaya, E Yılmaz, E Ersan… - 2020 - dspace.biruni.edu.tr
… respiratory syndrome coronavirus 2” (SARSCoV-2) is yet to be enlightened further. Inflammatory process along with the damage of the host’s immune system plays a pivotal role in all …
A Rubio-Casillas, RC Gupta, EM Redwan… - Exploration of …, 2022 - explorationpub.com
… ” refers to a scenario in which several cytokines released are harmful to the host [9, 38]. … of an excessive cytokinestorm [2]. It is worth noting that the production of numerous cytokines is …
… The hallmark of COVID-19 pathogenesis is the cytokinestorm with elevated levels of interleukin-6 (IL-6), IL-1β, tumor necrosis factor-alpha (TNF-α), chemokine (CC-motif) ligand 2 (…
AM Pisoschi, F Iordache, L Stanca… - Journal of Medicinal …, 2022 - ACS Publications
… Alleviating overproduction of reactive oxygen species and cytokinestorm in COVID-19 is … , cytokinestorm, hyperinflammation, and diminish the risk of organ failure. Direct antiviral roles …
RP Dellinger, MM Levy, CA Schorr… - Critical care …, 2021 - journals.lww.com
The last 50 years have been marked by increased understanding of the underpinnings of sepsis, its myriad manifestations and optimal approaches to therapy. The 50-year timeline that …
… The viral-provoked ACE2 downregulation aggravated a subsequent potentially lethal cytokinestorm. Both the tumor necrosis factor-alpha (TNF-α) receptor (TNFR), activated by the …
N Saksena, SR Bonam, M Miranda-Saksena - Frontiers in Genetics, 2021 - frontiersin.org
… system produces copious amounts of cytokines (ie, cytokinestorm), which damages the … edema, inflammation, hyper-proliferation, and cytokinestorm together causing ARDS (Figure 4). …
… and the ability to contribute to the cytokinestorm characteristic of COVID-19 (44). Aging is … increase inflammatory responses leading to the cytokinestorm for which the disease is …