[HTML][HTML] Genome-wide gene and pathway analysis

L Luo, G Peng, Y Zhu, H Dong, CI Amos… - European Journal of …, 2010 - nature.com
analysis: SNP, gene and pathway and suggest gene and pathway-based GWAS. In … in the
set of genes to be analyzed, we formulate the gene and pathway-based GWAS as the problem …

Using genomewide pathway analysis to unravel the etiology of complex diseases

CC Elbers, KR van Eijk, L Franke… - … Official Publication of …, 2009 - Wiley Online Library
… : To further evaluate whether the network analysis would bias our results toward certain well
studied pathway, we then performed pathway analysis on our original gene set without pre-…

[HTML][HTML] Pathway analysis of seven common diseases assessed by genome-wide association

A Torkamani, EJ Topol, NJ Schork - Genomics, 2008 - Elsevier
… We present a pathway analysis approach to … pathways implicated in disease predisposition
that would have not been revealed using standard single-locus GWAS statistical analysis

Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis

YH Lee, SC Bae, SJ Choi, JD Ji, GG Song - Molecular biology reports, 2012 - Springer
… However, there is no accepted way of comparing the various pathway analysisgenome
represents an important limitation of the use of the pathway-based approach for GWAS analysis. …

Implication of the immune system in Alzheimer's disease: evidence from genome-wide pathway analysis

JC Lambert, B Grenier-Boley… - Journal of …, 2010 - content.iospress.com
… In order to take into account these two sources of bias in the selected KEGG immune gene
pathways, we repeated an analysis in which each SNP was assigned to only one gene (…

[PDF][PDF] Integrating pathway analysis and genetics of gene expression for genome-wide association studies

H Zhong, X Yang, LM Kaplan, C Molony… - The American Journal of …, 2010 - cell.com
… Using genome-wide pathway analysis to unravel the etiology of complex diseases. Genet. …
Pathway analysis of seven common diseases assessed by genome-wide association. …

Statistical methods for pathway analysis of genome-wide data for association with complex genetic traits

P Holmans - Advances in genetics, 2010 - Elsevier
… This review describes the various types of statistical methods for pathway analysis, detailing
… power of pathway analyses, such as gene coverage and choice of pathways to analyze, are …

Genome-wide pathway analysis of breast cancer

YH Lee, JH Kim, GG Song - Tumor Biology, 2014 - Springer
… In the present pathway analysis, we used ICSNPathway analysis to identify candidate
SNPs, genes, and pathways that together suggested hypothetical biological mechanisms that …

Genome-wide pathway analysis in major depressive disorder

GG Song, JH Kim, YH Lee - Journal of Molecular Neuroscience, 2013 - Springer
… ICSNPathway analysis, which provided 16 hypothetical biological mechanisms. To our
knowledge, the several candidate genes and pathways identified by the pathway analysis in the …

Genome-wide pathway analysis of a genome-wide association study on multiple sclerosis

GG Song, SJ Choi, JD Ji, YH Lee - Molecular biology reports, 2013 - Springer
… studies, this analysis may cause a bias due to incomplete GWAS data. Thus we did not
perform pathway analysis without the significant genes/SPNPs. Nevertheless, pathway-based …