… imaging (MRI) markers of cSVD (2). CSVD is associated with an increased risk of stroke,
cognitive impairment, and … that blood–brain barrier (BBB) dysfunction is a contributing factor (4). …

Background/Aims: We evaluated the cerebrospinal fluid/serum albumin ratio (AR) and
kinetics of matrix metalloproteinase-9 (MMP-9) in blood as markers for blood-brain barrier (BBB) …

This article reviews current knowledge of the mechanisms underlying the initial hemorrhage
and secondary blood–brain barrier (BBB) dysfunction in primary spontaneous intracerebral …

… The T1W image before Gd-DTPA was subtracted from the images at each time point after
Gd-… for different brain regions. White matter hyperintensities were scored from the FLAIR image. …

… blood-brain barrier. We then developed a molecular imaging method to visualize MMP activity
in the brain … positron emission tomography (PET) imaging of MMP activity in patients with …

… of the tight junctions (TJ) in the blood–brain barrier (BBB). A number of changes have been
… and radiological biomarkers of severity of BBB dysfunction and its effects on outcomes after …

… An increase of the permeability of the blood-brain-barrier (BBB) represents a crucial step …
imaging (MRI). T 2 *-weighted gradient echo MRI (T 2 *w) and susceptibility-weighted imaging (…

… disorders, suitable measurements are required to demonstrate integrity and functional changes
at the interfaces between the blood and brain … BBB, and imaging modalities are available …

… We report a strongly positive correlation between the SPECT and DCE-MRI brain scan
assessment of BBB dysfunction. We are aware that the small number of patients reduces the …

… Brain capillaries are a key site of the blood–brain barrier (BBB). The capillary cross
section (large inset) shows a tightly sealed endothelium, which shares a common basement …