Bloodbrain barrier leakage is more widespread in patients with cerebral small vessel disease

CE Zhang, SM Wong, HJ van de Haar, J Staals… - Neurology, 2017 - AAN Enterprises
… We excluded 4 participants due to unsuccessful imaging or image artefacts, leaving 77
patients with cSVD (43 patients with lacunar stroke and 34 patients with mVCI) and 39 controls …

Blood–retina-barrier disruption accompanying bloodbrain-barrier dysfunction in posterior reversible encephalopathy syndrome

E Ozkan, R Gocmen, MA Topcuoglu… - Journal of the Neurological …, 2014 - Elsevier
… We present a case with blood–retina-barrier impairment during an episode of PRES. …
Imaging modalities sensitive for detection of blood-brain-barrier dysfunction, such as contrast …

The blood-brain barrier in health and chronic neurodegenerative disorders

BV Zlokovic - Neuron, 2008 - cell.com
… The blood-brain barrier (BBB) is a highly specialized brain endothelial structure of the fully
… In vivo multiphoton imaging of cortical blood flow in mice expressing green fluorescent …

Bloodbrain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis

R Topakian, TR Barrick, FA Howe… - Journal of Neurology …, 2010 - jnnp.bmj.com
… of the coregistered segmented images were computed such that each image voxel was
assigned to … to generate a brain mask image representing WML and NAWM at each image voxel. …

Addressing bloodbrain barrier impairment in Alzheimer's disease

C Sharma, H Woo, SR Kim - Biomedicines, 2022 - mdpi.com
… degree of inflammation in the brain or blood that can cause BBB dysfunction, leaks, or even
… We anticipate that imaging techniques such as 7T MRI and other technologies will increase …

PET-MRI nanoparticles imaging of bloodbrain barrier damage and modulation after stroke reperfusion

J Debatisse, OF Eker, O Wateau, TH Cho… - Brain …, 2020 - academic.oup.com
… or impaired bloodbrain barrier through combined passive and active processes. Imaging
and quantifying their transfer rate could better characterize bloodbrain barrier damage and …

[HTML][HTML] Blood-brain barrier dysfunction significantly correlates with serum matrix metalloproteinase-7 (MMP-7) following traumatic brain injury

P Nichols, J Urriola, S Miller, T Bjorkman, K Mahady… - NeuroImage: Clinical, 2021 - Elsevier
… 20 patients with a mild, moderate, or severe TBI underwent a DCE-MRI scan and BBB
dysfunction was interpreted from K Trans . K Trans is a measure of capillary permeability that …

Doxycycline prevents bloodbrain barrier dysfunction and microvascular hyperpermeability after traumatic brain injury

BD Robinson, CL Isbell, AR Melge, AM Lomas… - Scientific Reports, 2022 - nature.com
… (a) Intravital microscopic imaging of mouse brain pial venules demonstrating changes in
bloodbrain barrier/… The imaging was started 10 min after injury or drug administration. …

[HTML][HTML] Dysfunction of the blood-brain barrier in cerebral microbleeds: from bedside to bench

H Wang, C Zhang, Y Qiu, A Chen, Y Li, B Hu - Aging and disease, 2021 - ncbi.nlm.nih.gov
Cerebral microbleeds (CMBs) are a disorder of cerebralBlood-brain barrier (BBB)
dysfunction is considered to be the event … on imaging), hypointense, round lesions on T2-weighted …

Blood-brain barrier dysfunction in idiopathic intracranial hypertension

MM Hasan-Olive, HA Hansson, R Enger… - … of Neuropathology & …, 2019 - academic.oup.com
… The images were recorded with a FEI Tecnai 12 transmission electron microscope (FEI …
Eight bit images were subsequently analyzed using a MATLAB based toolbox (40), designed for …