Immunotherapies and immunomodulatory approaches in clinical trials-a mini review

M Iqbal Yatoo, Z Hamid, I Rather… - … immunotherapeutics, 2021 - Taylor & Francis
… 14 cytokine therapies Citation15,Citation16 and immune modulators are some of the
immunotherapeutic options … inflammatory cascade by modulating cytokine storm when most of the …

Immunomodulatory therapy for the management of severe COVID-19. Beyond the anti-viral therapy: A comprehensive review

J Alijotas-Reig, E Esteve-Valverde, C Belizna… - Autoimmunity …, 2020 - Elsevier
… response, the so-called “cytokine storm”. The reduction of this … can interrupt the storm of
inflammatory cytokines caused by … ], we think the IVIG option should be carefully analyzed before …

[HTML][HTML] Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies?

C Constantinescu, S Pasca, T Tat… - … for ImmunoTherapy …, 2020 - ncbi.nlm.nih.gov
… response syndrome following massive cytokine release into the … Thus, five of them possibly
having an option of subsequent … review, might be a therapeutic option for refractory CRS.8 …

A guide to immunotherapy for COVID-19

FL van de Veerdonk, E Giamarellos-Bourboulis… - Nature medicine, 2022 - nature.com
… Therefore, we aim to provide guidance on immunotherapeutic strategies that are supported
… will augment this guidance with possible treatment options for when patients fail to respond …

Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms

S Kang, T Kishimoto - Experimental & molecular medicine, 2021 - nature.com
… contributions of IL-6 signaling to the pathogenesis of several types of cytokine storms and
discuss potential therapeutic strategies for the management of cytokine storms, including those …

Immunobiology and immunotherapy of COVID‐19: A clinically updated overview

A Esmaeilzadeh, R Elahi - Journal of cellular physiology, 2021 - Wiley Online Library
cytokines could reduce the severity of the cytokine storm. Interventions that lead the immune
response through Th2-mediated immune responses are also among other options. These …

Cytokine storm and signaling pathways: pathogenesis of SARS‐CoV‐2 infection, managing and treatment strategies

R Kumar, K Gulia - 2021 - wlv.openrepository.com
… , an immunotherapeutic strategy will be effective for the suppression of cytokine storms and
… The option to counter the progression of cytokine storm can only be possible if a proper …

[HTML][HTML] Cytokine storm intervention in the early stages of COVID-19 pneumonia

X Sun, T Wang, D Cai, Z Hu, H Liao, L Zhi, H Wei… - Cytokine & growth factor …, 2020 - Elsevier
immunotherapy treatment at the time of diagnosis, in order to block the possibility of a
subsequent cytokine storm. … potential treatment options against the virus-induced cytokine storm. …

Continuous intravenous anakinra infusion to calm the cytokine storm in macrophage activation syndrome

LA Monteagudo, A Boothby… - ACR open rheumatology, 2020 - Wiley Online Library
… Clinicians often find, however, that these therapeutic options are not adequate, and … of
biologics and immunotherapies, case reports have described other therapeutic options for MAS, …

Immune signature of covid-19: In-depth reasons and consequences of the cytokine storm

P Niedźwiedzka-Rystwej, A Majchrzak… - International Journal of …, 2022 - mdpi.com
… has been associated with a cytokine storm (CS) syndrome in … CoV were also characterized
by a cytokine storm [6]. There are … the duality of the cytokine storm phenomenon in COVID-19, …