JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Heart Failure, 2021 - jacc.org
… dapagliflozin in chronic kidneydisease (CKD) patients, with and without heart failure (HF). … , end-stage kidneydisease, or death from kidney cause was similar in these 2 patient groups: …
P Fioretto, S Del Prato, JB Buse… - Diabetes, Obesity …, 2018 - Wiley Online Library
… Dapagliflozin is a selective inhibitor of sodium glucose co-… safety of dapagliflozin 10 mg vs placebo in patients with type 2 … 59 mL/min/1.73 m 2 ; chronic kidneydisease [CKD] stage 3A). …
Y Kurata, M Nangaku - Expert Review of Endocrinology & …, 2022 - Taylor & Francis
… the effect on individual kidneydiseases. Dapagliflozin reduced the risk of the primary composite endpoint by 71% (HR, 0.29; 95% CI, 0.12 to 0.73) in patients with IgAnephropathy (n = …
HJL Heerspink, AM Langkilde… - New England Journal of …, 2021 - discovery.ucl.ac.uk
… patients with or without type 2 diabetes and may explain the protective effects of dapagliflozin in chronic kidneydisease result… Our data indicate that the effects of dapagliflozin on all the …
JJV McMurray, DC Wheeler, BV Stefánsson, N Jongs… - Circulation, 2021 - Am Heart Assoc
… of dapagliflozin on the prespecified kidney and cardiovascular outcomes in patients with chronic kidneydisease … of cardiovascular disease, in the DAPA-CKD trial (Dapagliflozin and …
GM Chertow, P Vart, N Jongs, RD Toto… - Journal of the …, 2021 - journals.lww.com
… In this prespecified subgroup analysis of the DAPA-CKD trial, we show beneficial effects of dapagliflozin on kidney and cardiovascular end points in patients with stage 4 CKD at …
DC Wheeler, BV Stefánsson, N Jongs… - The lancet Diabetes & …, 2021 - thelancet.com
… in patients with chronic kidneydisease. We aimed to investigate the effects of dapagliflozin on kidney, … to underlying cause of chronic kidneydisease, reported as diabetic nephropathy, …
HJL Heerspink, N Jongs, GM Chertow… - The lancet Diabetes & …, 2021 - thelancet.com
… Dapagliflozin significantly slowed long-term eGFR decline in patients with chronic kidney disease … The mean difference in eGFR slope between patients treated with dapagliflozin versus …
… kidney effects of the SGLT2 inhibitor dapagliflozin in patients with proteinuric kidneydisease … Notably, in our previous pilot study with dapagliflozin in patients with proteinuria caused by …