… Cytokinestormsyndrome (CSS) has generally been … Cytokinestorms (CSs) are associated with various pathologies, … cytokine release and cell death pathways; certain cytokines, …
N Vaninov - Nature Reviews Immunology, 2020 - nature.com
… syndrome (ARDS) and robust cytokinestorm are the hallmark of severe COVID-19 cases. Using single-cell … strategies that target the myeloidcell compartment, such as IL-6 inhibitors, to …
YT Wang, A Sansone, A Smirnov, CL Stallings… - Autophagy, 2023 - Taylor & Francis
… in myeloidcells have been implicated in protecting mice in models of cytokinestormsyndromes (CSS), a more extensive genetic analysis of the autophagy pathway for this disorder has …
RQ Cron, G Goyal, WW Chatham - Annual Review of Medicine, 2023 - annualreviews.org
… stimulation and hypersecretion of proinflammatory cytokines by neoplastic cells (50). … A study of patients with acute myeloid leukemia undergoing induction chemotherapy found that …
PY Lee, RQ Cron - The Journal of Immunology, 2023 - journals.aai.org
… Instead, CpG DNA–induced MAS appears to be more dependent on myeloidcells. The excess production of IFN-γ is dependent on IL-12 primarily produced by inflammatory monocytes …
B Salomé, A Magen - Nature Reviews Immunology, 2020 - nature.com
… myeloidcells in COVID-19 Acute respiratory distress syndrome (ARDS) and robust cytokine storm … Using single-cell RNA sequencing of bronchoalveolar lavage fluid, this preprint study …
SW Canna, RQ Cron - Journal of Allergy and Clinical Immunology, 2020 - Elsevier
… on T- and NK-cell hyperactivation and production of … myeloidcells to promote histiocytosis, cytokinestorm, and life-threatening systemic immunopathology. BiTE, Bispecific T-cell …
… , tissue damage, and acute respiratory distress syndrome. Here, we discuss the sensing of … epithelial cells and circulating myeloidcells to release several pro-inflammatory cytokines [8, 9…
D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
… widely referred to as cytokine release syndrome (CRS) or, in particularly severe courses, cytokinestorm (CS)… (MDSC), members of a heterogeneous immature myeloidcell population, in …