… in the brain BM with normal aging affect all components and are specific to each brain region.
… on local microvascular function that impact the normal brain, as well as the progression of …

… the brain barriers change during aging and in AD and how these processes impact on brain
… In this review we will focus on the involvement of the brain barriers in aging and in AD. This …

… normal aging and various neurodegenerative diseases. In this review, we first briefly discuss
the aging … mechanisms of BBB breakdown associated with normal aging that further cause …

… BBB disruption in healthy aging The BBB undergoes a number of deleterious changes during
normal aging. Some of these changes may be adaptive but probably also contribute to age…

… of the blood–brain barrier and its supporting mechanisms and also on their alterations during
development, physiological aging … accumulate in the normal aging brain, increasing in both …

… MRI was used to quantify the blood-brain barrier (BBB) regional permeability K trans constant
in 12 regions of interest in the gray and white matter in the living human brain (A) including …

… cerebral blood vessels are critical for normal brain function; they form a blood-brain barrier
(BBB) that restricts fluid and entrained molecules from being transported into the brain from …

… that the mechanisms of BBB dysfunction that occurs in normal aging may result from the loss
of … in capillary dysfunction with normal aging. In the present study, the ageing effect was only …

… Blood–brain barrier (BBB) breakdown can disrupt nutrient supply and waste removal, which
… Dedicated DCE MRI studies in normal aging individuals are lacking, which could hamper …

… cognitive decline and hinder successful ageing is becoming increasingly important [4, 6]. …
even in elderly in the normal ageing spectrum [10]. The blood–brain barrier (BBB) is part of the …