The immunomodulatory role of cell-free approaches in SARS-coV-2-induced cytokine storm—A powerful therapeutic tool for COVID-19 patients

M Csobonyeiova, V Smolinska, S Harsanyi… - Biomedicines, 2023 - mdpi.com
… so-called cytokine storm (CS), which activates various inflammatory cytokines that damage
… have been intensively trying to investigate the best treatment options; however, only limited …

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
cytokine release in response to viral infection, a condition known as cytokine release
syndrome (CRS) or cytokine storm… timed anti-inflammatory therapeutic strategies could improve …

[HTML][HTML] Nanomedicine therapies modulating Macrophage Dysfunction: a potential strategy to attenuate Cytokine Storms in severe infections

J Liu, M Wan, CJ Lyon, TY Hu - Theranostics, 2020 - ncbi.nlm.nih.gov
… These studies suggest the potential utility of macrophage depletion by liposomes, or other …
potential to induce a cytokine storm and its associated pathological effects. To the best of our …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… an antiviral role, but a strong cytokine storm due to an unbalanced … to effectively suppress
cytokine storm is essential for … of IL-6 and has a therapeutic effect on cytokine storm caused

Potential therapeutic approaches for targeted inhibition of inflammatory cytokines following COVID-19 infection-induced cytokine storm

N Morgulchik, F Athanasopoulou, E Chu… - Interface …, 2021 - royalsocietypublishing.org
… pro-inflammatory cytokines in a specific manner can result in a potentstorm, and this review
will summarize and discuss advances in targeted therapies against cytokine storms induced

Targeting cytokine storm as the potential anti-viral therapy: Implications in regulating SARS-CoV-2 pathogenicity

S Maity, A Santra, AV Hebbani, S Pulakuntla… - Gene, 2023 - Elsevier
… an effective therapeutic strategy. This review focuses on the potential targeting of COVID-19
associated cytokine storm … The term cytokine storm itself as indicates a powerful activation or …

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… The development and optimization of therapeutic strategies aimed at targeting chemokines
and/or their receptors could add relevant tools for the clinical management of patients with …

Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications

C Pelaia, C Tinello, A Vatrella… - Therapeutic …, 2020 - journals.sagepub.com
… In other words, the massive and continuous release of proinflammatory cytokines and …
damage induced by the cytokine storm triggered by SARS-CoV-2, as well as on potential therapies

Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents

S Khadke, N Ahmed, N Ahmed, R Ratts, S Raju… - Virology journal, 2020 - Springer
… , although it may have increasing utility during later phases of disease … how best to manage
this illness and associated complications. Given the rapidly changing data, several therapies

Point‐of‐care detection of cytokines in cytokine storm management and beyond: Significance and challenges

G Liu, C Jiang, X Lin, Y Yang - View, 2021 - Wiley Online Library
… resource allocation and inform therapeutic options. Increasing evidence demonstrated that
… This assay may serve as a powerful tool for POC diagnosis of inflammation and infectious …