… inflammasome activation, the content … NLRP3 the inflammasome and GSDMD cleavage.
As such, the present review summarizes recent inhibitors of the NLRP3 inflammasome pathway …

… of NLRP3 inflammasome inhibitors and their therapeutic … therapeutic candidate for
stress-related mood disorders treatment. … for the NLRP3 inflammasome pathway compared with …

… to target the NLRP3 inflammasome pathway directly or … development targeting the NLRP3
inflammasome pathway. … a promising candidate as treatment for NLRP3 inflammasome …

… therapeutic candidates targeting the inflammasomes and their relevant components or
signaling pathways … act as a potent therapeutics against NLRP3 inflammasome-related cancers […

… of altering pathways not directly related to the NLRP3 inflammasome. This applies to
both cell-based assays and, in particular, any in vivo studies. Currently, the most well-characterized …

… of NLRP3 to inflammasome activation promises numerous … presuming the structure of
either of those clinical candidates. … Potassium efflux is the third route to NLRP3 inflammasome …

… of the NLRP3 inflammasome signaling pathway in autoimmune … NLRP3 inflammasome
complex may serve as a promising … as promising candidates for targeting treatment in the clinics. …

… : canonical, noncanonical, and alternative pathways (Figure 1). The progress of canonical …
(IC 50 = 0.003 μΜ) emerged as promising candidates, thereby demonstrating the potential of …

… mechanisms, and is a promising therapeutic target in immune-… In addition, we have also
summarized the candidate drugs … non-canonical pathways of NLRP3 inflammasome activation. …

… The NLRP3 inflammasome signaling pathway is activated … canonical and non-canonical
pathways in sterile inflammation or … stimuli, NLRP3 is intensively pursuit as a promising drug …