Potent and persistent antibody responses against the receptor-binding domain of SARS-CoV spike protein in recovered patients

Z Cao, L Liu, L Du, C Zhang, S Jiang, T Li, Y He - Virology journal, 2010 - Springer
… Serum samples from SARS patients Two panels of serum samples from the recovered
SARS patients were used in this study. The first panel of 35 samples were leftover from the …

Immunogenic profile of SARS-CoV-2 spike in individuals recovered from COVID-19

JA Juno, HX Tan, WS Lee, A Reynaldi, HG Kelly… - medRxiv, 2020 - medrxiv.org
… , recovered subjects exhibited robust cTFH responses to the SARS-CoV-2 spike protein, with
a median of 0.92% spike-… cross-reactive antibodies recovered from convalescent patients to …

… term persistence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-specific and neutralizing antibodies in recovered COVID-19 patients

J Chansaenroj, R Yorsaeng, J Puenpa… - PLoS …, 2022 - journals.plos.org
… the dynamics of SARS-CoV-2 antibodies, including anti-spike protein 1 (S1) … SARS-CoV-2
over time in a cohort of patients who were previously infected with the wild-type SARS-CoV-2. …

T-cell epitopes in severe acute respiratory syndrome (SARS) coronavirus spike protein elicit a specific T-cell immune response in patients who recover from SARS

YD Wang, WYF Sin, GB Xu, HH Yang, T Wong… - Journal of …, 2004 - Am Soc Microbiol
… the acute period of SARS (10). In the present study, we focused on anti-SARS-CoV immunity
in patients who had recovered from SARS but not in patients suffering acutely from SARS or …

Robust T cell response toward spike, membrane, and nucleocapsid SARS-CoV-2 proteins is not associated with recovery in critical COVID-19 patients

CJ Thieme, M Anft, K Paniskaki… - Cell Reports …, 2020 - cell.com
… (N-) proteins may define COVID-19 severity. Therefore, we compare the SARS-CoV-2-reactive
T cell responses in moderate, severe, and critical COVID-19 patients and unexposed …

Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients

B Zhang, Y Hu, L Chen, T Yau, Y Tong, J Hu, J Cai… - Cell research, 2020 - nature.com
… We found that the SARS-CoV-2 RBD contained four ID sites, IDd, IDe, IDf, … SARS-CoV-2
Spike protein shares 75.96% amino acid sequence identity with that of the SARS-CoV, we found

Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications

F Wu, A Wang, M Liu, Q Wang, J Chen, S Xia, Y Ling… - MedRxiv, 2020 - medrxiv.org
… We also measured the binding antibodies to the different domains (RBD, S1, and S2) of
SARS-CoV-2 spike protein in the plasma of these six patients. The kinetics of NAbs (right Y axis) …

Dynamic changes in anti-SARS-CoV-2 antibodies during SARS-CoV-2 infection and recovery from COVID-19

K Li, B Huang, M Wu, A Zhong, L Li, Y Cai… - Nature …, 2020 - nature.com
… findings of 1,850 patients to describe the dynamic changes of the total antibody, spike protein
(S… antibody levels of patients with confirmed SARS-CoV-2 infection and found that 39.6% of …

Persistent SARSCoV‐2 infection in patients seemingly recovered from COVID‐19

R Bussani, L Zentilin, R Correa, A Colliva… - The Journal of …, 2023 - Wiley Online Library
… In almost 90% of patients, we detected a large number … SARS-CoV-2 spike protein [5]. The
course of sign and symptom resolution in cases with moderate or severe disease who recover

Protective humoral and cellular immune responses to SARS-CoV-2 persist up to 1 year after recovery

C Feng, J Shi, Q Fan, Y Wang, H Huang, F Chen… - Nature …, 2021 - nature.com
… of patients, SARS-CoV-2 specific IgM and IgA levels decreased substantially to background
levels within 1 year. Spike-… antibodies against the SARS-CoV-2 RBD spike protein in plasma …