Mechanisms involved in Jurkat cell death induced by oleic and linoleic acids

MF Cury-Boaventura, CC Kanunfre, R Gorjão… - Clinical Nutrition, 2006 - Elsevier
BACKGROUND & AIMS: Previous study from our laboratory showed the toxicity of oleic (OA)
and linoleic acids (LA) on Jurkat and Raji cells and human lymphocytes in vitro. The …

Induction and modulation of apoptosis in neonatal monocytes by polyunsaturated fatty acids

B Sweeney, P Puri, DJ Reen - Journal of pediatric surgery, 2007 - Elsevier
Polyunsaturated fatty acids (PUFAs), known modulators of the immune response, are the
source of essential fatty acids in total parenteral nutrition–dependent patients. Critically ill …

Dietary n-3 polyunsaturated fatty acids promote activation-induced cell death in Th1-polarized murine CD4+ T-cells

KC Switzer, YY Fan, N Wang, DN McMurray… - Journal of lipid …, 2004 - ASBMB
Dietary n-3 PUFAs have been shown to attenuate T-cell-mediated inflammation. To
investigate whether dietary n-3 PUFAs promote activation-induced cell death (AICD) in …

Regulation of human lymphocyte proliferation by fatty acids

R Gorjao, MF Cury‐Boaventura… - Cell Biochemistry and …, 2007 - Wiley Online Library
In the present study, the effect of increasing concentrations of palmitic (PA, C16: 0), stearic
(SA, C18: 0), oleic (OA, C18: 1, n‐9), linoleic (LA, C18: 2n‐6), docosahexaenoic (DHA, C22 …

Induction of apoptosis and lipogenesis in human preadipocyte cell line by n −3 PUFAs

H Hanada, K Morikawa, K Hirota… - Cell biology …, 2011 - Wiley Online Library
We examined the effect of n− 3 PUFAs (polyunsaturated fatty acids) on the growth and
maturation of human preadipocyte cell line AML‐I. On day 3 of the culture, n− 3 fatty acids …

The effect of dietary lipid manipulation on murine splenic lymphocytes apoptosis and heat shock protein over expression

CR Carratelli, I Nuzzo, T Vitiello… - FEMS Immunology & …, 1999 - academic.oup.com
In this study, we kept BALB/c mice on a hyperlipidic diet for 120 days and then assessed the
predisposition to apoptosis and the appearance of heat shock protein (Hsp) on splenic …

Effect of medium/ω-6 long chain triglyceride-based emulsion on leucocyte death and inflammatory gene expression

MF Cury-Boaventura, R Gorjão… - Clinical & …, 2011 - academic.oup.com
Lipid emulsion (LE) containing medium/ω-6 long chain triglyceride-based emulsion (MCT/ω-
6 LCT LE) has been recommended in the place of ω-6 LCT-based emulsion to prevent …

Eicosapentaenoic and docosahexaenoic acids alter rat spleen leukocyte fatty acid composition and prostaglandin E2 production but have different effects on …

LD Peterson, NM Jeffery, F Thies, P Sanderson… - Lipids, 1998 - Wiley Online Library
Weanling rats were fed on high‐fat (178 g/kg) diets which contained 4.4 g α‐linolenic (ALA),
γ‐linolenic, arachidonic (ARA), eicosapentaenoic (EPA), or docosahexaenoic acid …

Different kinetic in incorporation and depletion of n− 3 fatty acids in erythrocytes and leukocytes of mice

H Mu, RL Thøgersen, K Maaetoft-Udsen, EM Straarup… - Lipids, 2006 - Springer
Abstract n− 3 PUFA are well known for their anti-inflammatory effects. However, there has
been only limited study on the kinetics of incorporation and depletion of n− 3 PUFA in …

Effect of fatty acids on leukocyte function

C Pompéia, LR Lopes, CK Miyasaka… - Brazilian Journal of …, 2000 - SciELO Brasil
Fatty acids have various effects on immune and inflammatory responses, acting as
intracellular and intercellular mediators. Polyunsaturated fatty acids (PUFAs) of the omega-3 …