Polyunsaturated fatty acids (PUFAs) and their metabolites are potent regulators of
inflammation. Generally, omega (n)-3 PUFAs are considered proresolving whereas n-6 …

Omega-3 fatty acids have diverse health benefits that are not clearly understood. In this
study we have examined the effects of the omega-3 fatty acid docosahexaenoic acid (DHA) …

Male CD-I mice were fed diets containing 10 wt% fat composed of a constant amount of n-6
polyunsaturated fatty acids (PUFA; safflower oil, 1.5 wt%) and increasing levels of n-3 PUFA …

We previously reported that docosahexaenoic acid (DHA) attenuated tumor necrosis factor
(TNF)-induced apoptosis in human monocytic U937 cells (J. Nutr. 130: 1095–1101, 2000). In …

Medium chain fatty acids (MCFA) can be more easily absorbed and supply energy more
rapidly than long chain fatty acids (LCFA). However, little is known about the inflammatory …

Cytokines and eicosanoids are important biologic mediators with tightly regulated
production. Overproduction contributes to pathogenesis of chronic and acute inflammatory …

Abstract Eicosapentaenoic acid (EPA; 20∶ 5n− 3) may reduce the cell number in cultured
leukemia/lymphoma cells owing to reduced cell proliferation, induction of cell death, or a …

Abstract Background Polyunsaturated fatty acids (PUFAs) can affect various functions of the
immune system including inflammatory responses. An oxidative burst of phagocytes …

Background: There is a growing body of evidence showing that dietary constituents and
lipids in particular, influence the function of the human immune system. However, although …

Enteral nutrition with eicosapentaenoic acid (EPA; 20: 5 n-3) and γ-linolenic acid (GLA; 18: 3
n-6) decreased pulmonary inflammation by reducing neutrophil counts and chemotactic …