[HTML][HTML] Cytokine storm and immunomodulatory therapy in COVID-19: role of chloroquine and anti-IL-6 monoclonal antibodies

M Zhao - International journal of antimicrobial agents, 2020 - ncbi.nlm.nih.gov
Severe acute respiratory syndrome coronavirus-2, the causative agent of coronavirus
disease 2019 (COVID-19), was declared a pandemic by the World Health Organization on …

Cytokine storm in COVID-19: pathogenesis and overview of anti-inflammatory agents used in treatment

M Soy, G Keser, P Atagündüz, F Tabak… - Clinical …, 2020 - Springer
COVID-19 infection has a heterogenous disease course; it may be asymptomatic or causes
only mild symptoms in the majority of the cases, while immunologic complications such as …

COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …

The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from …

W Zhang, Y Zhao, F Zhang, Q Wang, T Li, Z Liu… - Clinical …, 2020 - Elsevier
The pandemic outbreak of coronavirus disease 2019 (COVID-19) is rapidly spreading all
over the world. Reports from China showed that about 20% of patients developed severe …

Cytokine storm and the prospects for immunotherapy with COVID-19.

LH Calabrese - Cleveland Clinic journal of medicine, 2020 - europepmc.org
Knowledge about the pathobiology of SARS-CoV-2 as it interacts with immune defenses is
limited. SARS-CoV-2 is spread by droplets that come into contact with mucous membranes …

Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

Effective treatment of severe COVID-19 patients with tocilizumab

X Xu, M Han, T Li, W Sun, D Wang… - Proceedings of the …, 2020 - National Acad Sciences
After analyzing the immune characteristics of patients with severe coronavirus disease 2019
(COVID-19), we have identified that pathogenic T cells and inflammatory monocytes with …

Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes
coronavirus disease 2019 (COVID-19). As of 25 May 2020, the outbreak of COVID-19 has …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …

[PDF][PDF] Cytokine-targeted therapy in severely ill COVID-19 patients: options and cautions

M Rahmati, MA Moosavi - mortality, 2020 - researchgate.net
Dear Editor, Coronavirus disease 2019 (COVID-19) is an infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV-2) with the symptoms …