Most severe cases with COVID-19, especially those with pulmonary failure, are not a
consequence of viral burden and/or failure of the 'adaptive'immune response to subdue the …

COVID-19 has spread to most countries in the world. However, there are some striking
differences in how COVID-19 is behaving in different age groups. While data on COVID-19 …

Coronavirus disease-19 (COVID-19) describes a set of symptoms that develop following
infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Whilst …

The recent outbreak of COVID-19 has emerged as a major global health concern. Although
susceptible to infection, recent evidence indicates mostly asymptomatic or mild presentation …

Recent genome-wide association studies (GWASs) of COVID-19 patients of European
ancestry have identified genetic loci significantly associated with disease severity. Here, we …

The novel coronavirus disease 2019 (COVID-19) is spreading globally. Although its etiologic
agent is discovered as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

Coronavirus disease 2019 (COVID-19) is induced by SARS-CoV-2 and may arise as a
variety of clinical manifestations, ranging from an asymptomatic condition to a life …

Children, because of having an immature immune system, are usually more prone than the
adults to the microbial infections and have more severe symptoms, which is especially true …

Severe COVID-19 is rare in previously healthy individuals who are less than 50 years of
age, affecting probably no more than 1 in 1,000 such infected individuals. We suggest that …

The SARS-CoV-2 virus has complex and divergent immune alterations in differing hosts and
over disease evolution. Much of the nuanced COVID-19 disease immune dysregulation was …