Macrophage polarization is influenced by lipids, which also exert significant control over
macrophage functions. Lipids and their metabolites are players in intricate signaling …

Immune-mediated antitumor activities confront a variety of tumor-mediated defense
mechanisms. Here, we describe a new mechanism involving FFA that may allow breast …

OBJECTIVE:: The anti-inflammatory properties of parenteral nutrition might be improved by
enrichment with ω-3 polyunsaturated fatty acids (PUFAs), which are responsible for the …

Lipid metabolism in cancer cells has garnered increasing attention in recent decades.
Cancer cells thrive in hypoxic conditions, nutrient deficiency, and oxidative stress and …

Immunosuppressive myeloid cells play a major role in cancer by negatively regulating
immune responses, promoting tumor progression, and limiting the efficacy of cancer …

Macrophages are main players of the innate immune system. They show great
heterogeneity and play diverse functions that include support to development, sustenance of …

Simple Summary The evolution of cancer is strongly influenced by the context in which
tumor cells develop and grow, known as the tumor microenvironment (TME). The TME is …

Platelets can serve as “first responders” in cancer and metastasis. This is partly due to
bioactive lipid metabolism that drives both platelet and cancer biology. The two primary …

Simple Summary Cholesterol, lipids, and lipid metabolism are important in prostate cancer.
Lipid metabolism interacts with androgens which are of clear importance in prostate cancer …

Despite the wide range of available therapies, human colon cancers remain difficult to cure.
Evidence for efficient antitumoral immune responses to be raised is now widely accepted …