Maintaining blood-brain barrier (BBB) integrity is crucial for the homeostasis of the central
nervous system. Structurally comprising the BBB, brain endothelial cells interact with …

Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

The blood-brain barrier (BBB), which is located at the interface between the central nervous
system (CNS) and the circulatory system, is instrumental in establishing and maintaining the …

Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …

Abstract Purpose of Review This review aims to provide an overview of neuroinflammation
in ischemic and hemorrhagic stroke, including recent findings on the mechanisms and …

The blood‐brain barrier (BBB) is a highly regulated interface that separates the peripheral
circulation and the brain. It plays a vital role in regulating the trafficking of solutes, fluid, and …

Ischemic stroke is characterized by the disruption of cerebral blood flow (CBF). This
reduction of CBF results in energy failure and secondary biochemical disturbances, eliciting …

Despite the enormous progress in the understanding of the course of the ischemic stroke
over the last few decades, a therapy that effectively protects neurovascular units (NVUs) and …

Stroke is one of the leading causes of mortality and morbidity worldwide. The bloodbrain
barrier (BBB) is a characteristic structure of microvessel within the brain. Under normal …