Among patients suffering from coronavirus disease 2019 (COVID-19) syndrome, one of the
worst possible scenarios is represented by the critical lung damage caused by the severe …

Elevated concentrations of interleukin-6 have been demonstrated to be an important key
factor in COVID-19 host immune impairment. It represents an important prognostic factor of …

Introduction: Corona virus is a group of viruses that cause diseases in mammals and birds.
In humans, these families of viruses can cause respiratory infections from a mild form to fatal …

Currently, the world is facing the pandemic of a novel strain of beta‐coronavirus known as
severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Acute respiratory distress …

Background In the absence of highly effective antiviral therapies against SARS-CoV-2, it is
crucial to counter the known pathophysiological causes of severe COVID-19. Evaluating the …

Background The clinical presentation of SARS-CoV-2 infection ranges from mild symptoms
to severe complications, including acute respiratory distress syndrome. In this syndrome …

The lung is a key target of the cytokine storm that can be triggered by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for the widespread clinical …

Objectives Cytokine release syndrome with elevated interleukin-6 (IL-6) levels is associated
with multiorgan damage and death in severe coronavirus disease 2019 (COVID-19). Our …

Life-threatening COVID-19 is associated with strong inflammation, where an IL-6-driven
cytokine storm appears to be a cornerstone for enhanced pathology. Nonetheless, the …

A newly identified virus appeared in Wuhan, China, in December 2019, was named severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and caused the coronavirus …