[HTML][HTML] Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome

S Lin, Y Zhao, D Zhou, F Zhou, F Xu - Genes & Diseases, 2020 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) was first identified in China at the end of
2019. Acute respiratory distress syndrome (ARDS) represents the most common and serious …

[HTML][HTML] Immunopathology of Hyperinflammation in COVID-19

JN Gustine, D Jones - The American journal of pathology, 2021 - Elsevier
The rapid spread of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome–coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented …

Inflammatory pathways in COVID‐19: mechanism and therapeutic interventions

Y Jiang, T Zhao, X Zhou, Y Xiang… - MedComm, 2022 - Wiley Online Library
Abstract The 2019 coronavirus disease (COVID‐19) pandemic has become a global crisis.
In the immunopathogenesis of COVID‐19, SARS‐CoV‐2 infection induces an excessive …

Could SARS-CoV-2-induced hyperinflammation magnify the severity of coronavirus disease (CoViD-19) leading to acute respiratory distress syndrome?

ASS Girija, EM Shankar, M Larsson - Frontiers in immunology, 2020 - frontiersin.org
The exaggerated immune response induced in the lower respiratory tract against
coronaviruses (CoVs), including CoViD-19 (2019-nCoV), appears to contribute to the …

Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states

LF Schimke, AHC Marques, GC Baiocchi… - Cells, 2022 - mdpi.com
Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …

Characterisation of the pro-inflammatory cytokine signature in severe COVID-19

HC Hawerkamp, AH Dyer, ND Patil… - Frontiers in …, 2023 - frontiersin.org
Clinical outcomes from infection with SARS-CoV-2, the cause of the COVID-19 pandemic,
are remarkably variable ranging from asymptomatic infection to severe pneumonia and …

Dysregulation of the immune response in coronavirus disease 2019

L Mohamed Khosroshahi, N Rezaei - Cell Biology International, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine
storm in the pulmonary tissue by releasing various types of mediators, leading to acute …

Lessons learned to date on COVID-19 hyperinflammatory syndrome: considerations for interventions to mitigate SARS-CoV-2 viral infection and detrimental …

M Cardone, M Yano, AS Rosenberg… - Frontiers in …, 2020 - frontiersin.org
The first case of human transmission of SARS-CoV-2 was reported in China in December
2019. A few months later, this viral infection had spread worldwide and became a pandemic …

Dysregulated immune responses in SARS-CoV-2-infected patients: a comprehensive overview

I Kudryavtsev, A Rubinstein, A Golovkin, O Kalinina… - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in
humans more than two years ago and caused an unprecedented socio-economic burden on …

COVID-19: inflammatory profile

Y Wang, S Perlman - Annual review of medicine, 2022 - annualreviews.org
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), has resulted in a pandemic that has had widespread …