Background: The Coronavirus Disease 2019 (COVID-19) is becoming the major health
issue in recent human history with thousands of deaths and millions of cases worldwide …

Abstract Angiotensin-converting enzyme 2 (ACE2) has been recognized as a potential entry
receptor for SARS-CoV-2 infection. Binding of SARS-CoV-2 to ACE2 allows engagement …

The renin-angiotensin system (RAS) is crucial for the physiology and pathology of all the
organs. Angiotensin-converting enzyme 2 (ACE2) maintains the homeostasis of RAS as a …

COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. Angiotensin-
converting enzyme 2 (ACE2) is not only an enzyme but also a functional receptor on cell …

The emergency of SARS-CoV-2 in China started a novel challenge to the scientific
community. As the virus turns pandemic, scientists try to map the cellular mechanisms and …

Fever in infections correlates with inflammation, macrophage infiltration into the affected
organ, macrophage activation, and release of cytokines involved in immune response …

A massive worldwide vaccination campaign constitutes the main tool against the COVID-19
pandemic. However, drug treatments are also necessary. Antivirals are the most frequently …

Abstract Angiotensin-converting enzyme-2 (ACE2) has been recognized as the binding
receptor for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that infects …

Abstract Angiotensin converting enzyme-2 (ACE2) receptors mediate the entry into the cell
of three strains of coronavirus: SARS-CoV, NL63 and SARS-CoV-2. ACE2 receptors are …

OBJECTIVE: In human pathology, SARS-CoV-2 utilizes multiple molecular pathways to
determine structural and biochemical changes within the different organs and cell types. The …