Innate immunology in COVID-19—a living review. Part II: dysregulated inflammation drives immunopathology

PRS Rodrigues, A Alrubayyi, E Pring… - Oxford open …, 2020 - academic.oup.com
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a global health crisis and will …

Innate immunity in protection and pathogenesis during coronavirus infections and COVID-19

RKS Malireddi, BR Sharma… - Annual Review of …, 2024 - annualreviews.org
The COVID-19 pandemic was caused by the recently emerged β-coronavirus SARS-CoV-2.
SARS-CoV-2 has had a catastrophic impact, resulting in nearly 7 million fatalities worldwide …

Innate immune and inflammatory responses to SARS-CoV-2: Implications for COVID-19

SA Lowery, A Sariol, S Perlman - Cell Host & Microbe, 2021 - cell.com
COVID-19 can result in severe disease characterized by significant immunopathology that is
spurred by an exuberant, yet dysregulated, innate immune response with a poor adaptive …

The innate immune system: fighting on the front lines or fanning the flames of COVID-19?

JL McKechnie, CA Blish - Cell host & microbe, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS-CoV-2 has had
devastating global impacts and will continue to have dramatic effects on public health for …

Innate immunity, cytokine storm, and inflammatory cell death in COVID-19

R Karki, TD Kanneganti - Journal of Translational Medicine, 2022 - Springer
The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …

[HTML][HTML] An impaired inflammatory and innate immune response in COVID-19

SH Park - Molecules and cells, 2021 - Elsevier
The recent appearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has affected millions of people around the world and caused a global pandemic of …

Dysregulated innate immune and inflammatory responses in SARS-CoV-2 infection and COVID-19 severity

P Ghosh, S Nagaraja, S Basavaraju… - Critical Reviews™ in …, 2021 - dl.begellhouse.com
Pathogenic coronaviruses (CoVs) have caused human respiratory infections and severe
disease outbreaks in the past two decades. Recent severe acute respiratory syndrome …

[HTML][HTML] COVID-19 and the human innate immune system

JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …

[PDF][PDF] Innate immunity in COVID-19: Drivers of pathogenesis and potential therapeutic targets

V Ruenjaiman, N Hirankarn… - Asian Pacific journal of …, 2021 - apjai-journal.org
A novel severe acute respiratory syndrome COVID-19 caused by coronavirus SARS-CoV-2
has been confirmed to infect more than 100 million people globally, with mortality reaching …

SARS-CoV-2 and innate immunity: the good, the bad, and the “goldilocks”

BL Sievers, MTK Cheng, K Csiba, B Meng… - Cellular & Molecular …, 2024 - nature.com
An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of
immunity. Knowledge about this interplay can not only help us identify biological …