Insult-associated blood–brain barrier leakage is strongly suggested to be a key step during
epileptogenesis. In this study, we used three non-invasive translational imaging modalities …

The blood–brain barrier (BBB) plays an important role in the homeostasis of the brain. BBB
dysfunction has been implicated in the pathophysiology of various neurological disorders …

A biomarker that will enable the identification of patients at high-risk for developing post-
injury epilepsy is critically required. Microvascular pathology and related blood–brain barrier …

Dysfunction of the blood–brain barrier (BBB) is one of the major pathophysiological
consequences of epilepsy. The increase in the permeability caused by BBB failure is …

Increased permeability of the blood–brain barrier (BBB) following cerebral injury results in
regional extravasation of plasma proteins and can critically contribute to the pathogenesis of …

Recent animal experiments indicate a critical role for opening of the blood‐brain barrier
(BBB) in the pathogenesis of post‐traumatic epilepsy (PTE). This study aimed to investigate …

Background Traumatic brain injury (TBI) causes 10–20% of acquired epilepsy, which
typically develops within 2 years post-injury with poorly understood mechanisms. We …

Background: Traumatic brain injury (TBI) is an important cause of focal epilepsy. Animal
experiments indicate that disruption of the blood–brain barrier (BBB) plays a critical role in …

The blood–brain barrier (BBB), a unique anatomical and physiological interface between the
central nervous system (CNS) and the peripheral circulation, is essential for the function of …

Leakage of the blood–brain barrier (BBB) is associated with various neurological disorders,
including temporal lobe epilepsy (TLE). However, it is not known whether alterations of the …