In vivo studies have shown that blood–brain barrier (BBB) dysfunction is involved in the
course of Parkinson's disease (PD). However, these have lacked either anatomic definition …

Parkinson's disease (PD) is associated with a loss of neurons from the midbrain. The cause
of PD is unknown, but it is established that certain neurotoxins can cause similar syndromes …

Background Blood–brain barrier (BBB) disruption has been noted in animal models of
Parkinson's disease (PD) and forms the basis of the vascular hypothesis of …

[Frontiers in Bioscience 19, 272-280, January 1, 2014] 272 Disruption of the blood-brain barrier
in parkinson’s disease: curse Page 1 [Frontiers in Bioscience 19, 272-280, January 1, 2014] 272 …

Decreased blood–brain barrier (BBB) efflux function of the P-glycoprotein (P-gp) transport
system could facilitate the accumulation of toxic compounds in the brain, increasing the risk …

The blood–brain barrier (BBB) is a tightly regulated barrier in the central nervous system.
Though the BBB is thought to be intact during neurodegenerative diseases such as …

The blood–brain barrier (BBB) regulates differing needs of the various brain regions by
controlling transport of blood-borne components from the neurovascular circulation into the …

The adult quiescent blood–brain barrier (BBB), a structure organised by endothelial cells
through interactions with pericytes, astrocytes, neurons and microglia in the neurovascular …

The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Recent studies suggest that the function of the blood–brain barrier (BBB) is not static under
normal physiologic conditions and is likely altered in neurodegenerative disease. Prevailing …