Simple Summary The evolution of cancer is strongly influenced by the context in which
tumor cells develop and grow, known as the tumor microenvironment (TME). The TME is …

Bioactive lipids are essential components of human cells and tissues. As discussed in this
review, the cancer lipidome is diverse and malleable, with the ability to promote or inhibit …

Cancer is a process involving cell mutation, increased proliferation, invasion, and
metastasis. Over the years, this condition has represented one of the most concerning health …

Inflammation is a recognized hallmark of cancer that contributes to the development and
progression of colorectal cancer (CRC). Anti-inflammatory drugs currently used for the …

Inflammation is considered an enabling feature of cancer. Besides the persistence of
inflammatory stimuli, also defective mechanisms of resolution can lead to chronic …

Polyunsaturated fatty acids (PUFAs) are enzymatically converted to a variety of bioactive
products through insertion of molecular oxygen. PUFA-derived mediators can have either …

The resolution of inflammation has emerged as a critical endogenous process that protects
host tissues from prolonged or excessive inflammation that can become chronic. Failure of …

Inflammation is a fundamental physiological response orchestrated by innate immune cells
to restore tissue homeostasis. Specialized pro-resolving mediators (SPMs) are involved in …

Unresolved inflammation is a pathological consequence of persistent inflammatory stimulus
and perturbation in regulatory mechanisms. It increases the risk of tumour development and …

Introduction ω-3 Polyunsaturated fatty acids (PUFAs) have a range of health benefits,
including anticancer activity, and are converted to lipid mediators that could be adapted into …