A combinational approach to restore cytokine balance and to inhibit virus growth may promote patient recovery in severe COVID-19 cases

A Mahmud-Al-Rafat, MMH Asim, AW Taylor-Robinson… - Cytokine, 2020 - Elsevier
The COVID-19 pandemic has led to twin public health and economic crises around the
world. Not only has it cost hundreds of thousands of lives but also severely impacted …

The basis of complications in the context of SARS-CoV-2 infection: pathological activation of ADAM17

S Jiang, H Yang, Z Sun, Y Zhang, Y Li, J Li - Biochemical and Biophysical …, 2023 - Elsevier
The virulence of SARS-CoV-2 decreases with increasing infectivity, the primary approaches
for antiviral treatments will be preventing or minimizing the complications resulting from virus …

[HTML][HTML] Intricate relationship between SARS-CoV-2–induced shedding and cytokine storm generation: A signaling inflammatory pathway augmenting COVID-19

MB Moftah, A Eswayah - Health Sciences Review, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), through its ability to
induce cytokine release syndrome, can set up a generalized inflammatory response …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

[PDF][PDF] An update on cytokine storm in covid-19 infection: Pivotal to the survival of the patients

EI Obeagu, S Hamisi, UO Bunu - Int. J. Adv. Res. Biol. Sci, 2023 - researchgate.net
The immune system protects the host organism from exogenous and endogenouspathogens
. A finely tuned and balanced array of cytokines, coagulation factors, andcomplement …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

[PDF][PDF] Treatment of the Cytokine Storm in COVID-19

B Halacli, A Topeli - J Crit Intensive Care, 2020 - researchgate.net
Cytokine storm has been proposed as the basis of the pathophysiological process of COVID-
19 caused by SARS-CoV-2. Cytokine storm, generally known as excessive or uncontrolled …

[HTML][HTML] Management of hyperinflammation in COVID-19 patients

B Suberviola, EC Fito - Revista Española de Quimioterapia, 2022 - ncbi.nlm.nih.gov
In response to SARS-CoV-2 infection, the immune system physiologically upregulates to try
to clear the virus from the body; failure to compensate for this inflammatory response with an …

Plasma cytokines in patients with COVID-19 during acute phase of the disease and following complete recovery

N Arsentieva, N Liubimova, O Batsunov, Z Korobova… - 2021 - covid19.neicon.ru
COVID-19, an infection caused by the new coronavirus SARS-CoV-2, is associated with a
number of pathophysiological mechanisms, mobilizing a wide spectrum of biomolecules …

[HTML][HTML] The cytokine storm in COVID-19: the strongest link to morbidity and mortality in the current epidemic

M Basheer, E Saad, N Assy - COVID, 2022 - mdpi.com
COVID-19 is an infectious disease caused by the SARS-CoV-2 virus. The clinical
presentations of the SARS-CoV-2 infection are widely variable and treatment strategies for …