An inter-correlated cytokine network identified at the center of cytokine storm predicted COVID-19 prognosis

Y Liu, D Chen, J Hou, H Li, D Cao, M Guo, Y Ling… - Cytokine, 2021 - Elsevier
The hyper-inflammatory response is thought to be a major cause of acute respiratory
distress syndrome (ARDS) in patients with COVID-19. Although multiple cytokines are …

Longitudinal cytokine profile in patients with mild to critical COVID-19

L Ling, Z Chen, G Lui, CK Wong, WT Wong… - Frontiers in …, 2021 - frontiersin.org
The cytokine release syndrome has been proposed as the driver of inflammation in
coronavirus disease 2019 (COVID-19). However, studies on longitudinal cytokine profiles in …

Features of cytokine storm identified by distinguishing clinical manifestations in COVID-19

WX Shen, RC Luo, JQ Wang, ZS Chen - Frontiers in public health, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is caused by a new coronavirus, namely severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is currently spreading all over …

A deep look into COVID-19 severity through dynamic changes in blood cytokine levels

DA Kleymenov, EN Bykonia, LI Popova… - Frontiers in …, 2021 - frontiersin.org
An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of
disease severity and mortality in patients with COVID-19. Longitudinal analysis of cytokine …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

Differential cytokine signatures of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza infection highlight key differences in pathobiology

AH Karaba, W Zhou, LL Hsieh… - Clinical Infectious …, 2022 - academic.oup.com
Background Several inflammatory cytokines are upregulated in severe coronavirus disease
2019 (COVID-19). We compared cytokines in COVID-19 versus influenza to define …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Cytokine signature and COVID-19 prediction models in the two waves of pandemics

S Cabaro, V D'Esposito, T Di Matola, S Sale… - Scientific Reports, 2021 - nature.com
In Europe, multiple waves of infections with SARS-CoV-2 (COVID-19) have been observed.
Here, we have investigated whether common patterns of cytokines could be detected in …

The Role of Inflammatory Cytokines (Interleukin-1 and Interleukin-6) as a Potential Biomarker in the Different Stages of COVID-19 (Mild, Severe, and Critical)

M Ghofrani Nezhad, G Jami, O Kooshkaki… - Journal of Interferon & …, 2023 - liebertpub.com
Cytokine storm refers to the overproduction of immune and inflammatory cells and their
proteins (cytokines)[interleukin (IL)-1 and IL-6] causing acute respiratory distress syndrome …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …