The gastrointestinal tract is an alternative route for SARS-CoV-2 infection in a nonhuman primate model

L Jiao, H Li, J Xu, M Yang, C Ma, J Li, S Zhao, H Wang… - Gastroenterology, 2021 - Elsevier
Background & Aims Gastrointestinal (GI) manifestations have been increasingly reported in
patients with coronavirus disease 2019 (COVID-19). However, the roles of the GI tract in …

[HTML][HTML] SARS-CoV-2 induces a more robust innate immune response and replicates less efficiently than SARS-CoV in the human intestines: an ex vivo study with …

H Chu, JFW Chan, Y Wang, TTT Yuen, Y Chai… - Cellular and molecular …, 2021 - Elsevier
Abstract Background And Aims Besides prominent respiratory involvement, gastrointestinal
manifestations are commonly reported in Coronavirus Disease 2019 (COVID-19) patients …

Intestinal host response to SARS-CoV-2 infection and COVID-19 outcomes in patients with gastrointestinal symptoms

AE Livanos, D Jha, F Cossarini, AS Gonzalez-Reiche… - Gastroenterology, 2021 - Elsevier
Background & Aims Given that gastrointestinal (GI) symptoms are a prominent
extrapulmonary manifestation of COVID-19, we investigated intestinal infection with SARS …

Potential intestinal infection and faecal–oral transmission of SARS-CoV-2

M Guo, W Tao, RA Flavell, S Zhu - Nature reviews Gastroenterology & …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …

Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells

M Lehmann, K Allers, C Heldt, J Meinhardt… - Mucosal …, 2021 - nature.com
The SARS-CoV-2 pandemic has so far claimed over three and a half million lives worldwide.
Though the SARS-CoV-2 mediated disease COVID-19 has first been characterized by an …

[HTML][HTML] COVID-19 and the digestive system

C Ma, Y Cong, H Zhang - Official journal of the American College …, 2020 - journals.lww.com
The outbreak of novel coronavirus pneumonia in 2019 (Coronavirus disease 2019 [COVID-
19]) is now threatening global public health. Although COVID-19 is principally defined by its …

[PDF][PDF] COVID-19, coronavirus, SARS-CoV-2 and the small bowel

K Mönkemüller, L Fry, S Rickes - Rev Esp Enferm Dig, 2020 - online.reed.es
Although SARS-CoV-2 may primarily enter the cells of the lungs, the small bowel may also
be an important entry or interaction site, as the enterocytes are rich in angiotensin converting …

Potential causes and consequences of gastrointestinal disorders during a SARS-CoV-2 infection

F Trottein, H Sokol - Cell reports, 2020 - cell.com
Coronaviruses cause several human diseases, including severe acute respiratory
syndrome. The global coronavirus disease 2019 (COVID-19) pandemic has become a huge …

[HTML][HTML] Gastrointestinal symptoms, pathophysiology, and treatment in COVID-19

J Zhang, S Garrett, J Sun - Genes & diseases, 2021 - Elsevier
Abstract The novel coronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) has emerged and is responsible for the Coronavirus Disease 2019 global pandemic …

Single‐cell analyses reveal SARS‐CoV‐2 interference with intrinsic immune response in the human gut

S Triana, C Metz‐Zumaran, C Ramirez… - Molecular systems …, 2021 - embopress.org
Exacerbated pro‐inflammatory immune response contributes to COVID‐19 pathology.
However, despite the mounting evidence about SARS‐CoV‐2 infecting the human gut, little …