COVID-19: hemoglobin, iron, and hypoxia beyond inflammation. A narrative review

A Cavezzi, E Troiani, S Corrao - Clinics and practice, 2020 - mdpi.com
Coronavirus disease-19 (COVID-19) has been regarded as an infective-inflammatory
disease, which affects mainly lungs. More recently, a multi-organ involvement has been …

Prevalence and predictive value of anemia and dysregulated iron homeostasis in patients with COVID-19 infection

R Bellmann-Weiler, L Lanser, R Barket… - Journal of clinical …, 2020 - mdpi.com
Infections with SARS-CoV-2 can result in severe clinical manifestations. As such patients
present with systemic inflammation, we studied the prevalence and predictive value of …

Anemia and iron metabolism in COVID-19: a systematic review and meta-analysis

PE Taneri, SA Gómez-Ochoa, E Llanaj… - European journal of …, 2020 - Springer
Iron metabolism and anemia may play an important role in multiple organ dysfunction
syndrome in Coronavirus disease 2019 (COVID-19). We conducted a systematic review and …

Dynamics in anemia development and dysregulation of iron homeostasis in hospitalized patients with COVID-19

L Lanser, FR Burkert, R Bellmann-Weiler, A Schroll… - Metabolites, 2021 - mdpi.com
Anemia and disturbances of iron metabolism are frequently encountered in patients with
COVID-19 and associated with an adverse clinical course. We retrospectively analyzed 645 …

Persisting alterations of iron homeostasis in COVID-19 are associated with non-resolving lung pathologies and poor patients' performance: a prospective …

T Sonnweber, A Boehm, S Sahanic, A Pizzini… - Respiratory …, 2020 - Springer
Background Severe coronavirus disease 2019 (COVID-19) is frequently associated with
hyperinflammation and hyperferritinemia. The latter is related to increased mortality in …

Anemia in patients with Covid-19: pathogenesis and clinical significance

G Bergamaschi, F Borrelli de Andreis, N Aronico… - Clinical and …, 2021 - Springer
COVID-19 patients typically present with lower airway disease, although involvement of
other organ systems is usually the rule. Hematological manifestations such as …

COVID-19 and hemoglobinopathies: a systematic review of clinical presentations, investigations, and outcomes

JX Lee, WK Chieng, SCD Lau, CE Tan - Frontiers in Medicine, 2021 - frontiersin.org
This systematic review aimed to provide an overview of the clinical profile and outcome of
COVID-19 infection in patients with hemoglobinopathy. The rate of COVID-19 mortality and …

Iron and iron-related proteins in COVID-19

E Suriawinata, KJ Mehta - Clinical and experimental medicine, 2023 - Springer
COVID-19 can cause detrimental effects on health. Vaccines have helped in reducing
disease severity and transmission but their long-term effects on health and effectiveness …

Iron dysregulation and inflammatory stress erythropoiesis associates with long-term outcome of COVID-19

AL Hanson, MP Mulè, H Ruffieux, F Mescia… - Nature …, 2024 - nature.com
Persistent symptoms following SARS-CoV-2 infection are increasingly reported, although
the drivers of post-acute sequelae (PASC) of COVID-19 are unclear. Here we assessed 214 …

Hypoferremia is associated with increased hospitalization and oxygen demand in COVID-19 patients

T Hippchen, S Altamura, MU Muckenthaler… - Hemasphere, 2020 - journals.lww.com
Iron metabolism might play a crucial role in cytokine release syndrome in COVID-19
patients. Therefore, we assessed iron metabolism markers in COVID-19 patients for their …