α, β-Unsaturated chalcone moieties and quinoline scaffolds play an important role in
medicinal chemistry, especially in the identification and development of potential anticancer …

The emergence of drug resistance and low specificity with side effects are the significant
challenges in pharmaceutical sectors for control of cancer nowadays. Notwithstanding, this …

The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …

Quinoline heterocycles have been considered important structures due to their diverse
applications in organic synthesis, coordination chemistry, as well as in the fields of drug …

Quinoline is a versatile pharmacophore, a privileged scaffold and an outstanding fused
heterocyclic compound with a wide range of pharmacological prospective such as …

A new series of quinoline-chalcone hybrids was synthesized. The structures of these
compounds were characterized by spectroscopic methods including 1 H and 13 CNMR and …

New quinoline/chalcone hybrids containing 1, 2, 4-triazole moiety have been designed,
synthesized and their structures elucidated and confirmed by various spectroscopic …

The global pandemic of drug-sensitive cancers and the increasing threat from drug-resistant
cancers make an urgent need to develop more effective anti-cancer candidates. Quinolone …

A series of quinoline-chalcone hybrids was designed as potential anti-cancer agents,
synthesized and evaluated. Different cytotoxic assays revealed that compounds …

Quinoline (1-azanaphthalene) is a heterocyclic aromatic nitrogen compound characterized
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …