Epigenetic clocks for mice were generated based on deep-sequencing analysis of the
methylome. Here, we demonstrate that site-specific analysis of DNA methylation levels by …

Age-associated DNA methylation reflects aspect of biological aging—therefore epigenetic
clocks for mice can elucidate how the aging process in this model organism is affected by …

Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …

Robust biomarkers of aging have been developed from DNA methylation in humans and
more recently, in mice. This study aimed to generate a novel epigenetic clock in rats—a …

Age predictors based on DNA methylation levels at a small set of CpG sites, DNAm clocks,
have been developed for humans and extended to several other species. Three currently …

Human DNA-methylation data have been used to develop highly accurate biomarkers of
aging (" epigenetic clocks"). Recent studies demonstrate that similar epigenetic clocks for …

Epigenetic clocks were initially developed to track chronological age, but accumulating
evidence indicates that they can also predict biological age. They are usually based on the …

Background DNA methylation changes at a discrete set of sites in the human genome are
predictive of chronological and biological age. However, it is not known whether these …

Background Age-associated DNA methylation changes provide a promising biomarker for
the aging process. While genome-wide DNA methylation profiles enable robust age …

Young blood plasma is known to confer beneficial effects on various organs in mice.
However, it was not known whether young plasma rejuvenates cells and tissues at the …