[HTML][HTML] Pyroptotic cell death in SARS-CoV-2 infection: revealing its roles during the immunopathogenesis of COVID-19

M Wang, W Chang, L Zhang… - International Journal of …, 2022 - ncbi.nlm.nih.gov
The rapid dissemination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
the causative agent of coronavirus disease 2019 (COVID-19), remains a global public health …

SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes

AC Ferreira, VC Soares… - Cell death …, 2021 - nature.com
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
associated with leukopenia and uncontrolled inflammatory response in critically ill patients …

Therapy targets SARS-CoV-2 infection-induced cell death

Z Zhu, J Shi, L Li, J Wang, Y Zhao, H Ma - Frontiers in Immunology, 2022 - frontiersin.org
Coronavirus Disease 2019 (COVID-19) caused by SARS-CoV-2 has become a global
health issue. The clinical presentation of COVID-19 is highly variable, ranging from …

Cell pyroptosis, a potential pathogenic mechanism of 2019-nCoV infection

M Yang - Available at SSRN 3527420, 2020 - papers.ssrn.com
nCoV is a novel coronavirus named in 2019. The number of people suffering from the virus
kept increasing from China to the world. The initial infection characters of 2019-nCoV has …

Cell death in coronavirus infections: Uncovering its role during COVID-19

A Paolini, R Borella, S De Biasi, A Neroni, M Mattioli… - Cells, 2021 - mdpi.com
Cell death mechanisms are crucial to maintain an appropriate environment for the
functionality of healthy cells. However, during viral infections, dysregulation of these …

Pyroptosis and its role in SARS-CoV-2 infection

ZA Bittner, M Schrader, SE George, R Amann - Cells, 2022 - mdpi.com
The pore-forming inflammatory cell death pathway, pyroptosis, was first described in the
early 1990s and its role in health and disease has been intensively studied since. The …

Differential activation of programmed cell death in patients with severe SARS-CoV-2 infection

AN Riegler, P Benson, K Long, SM Leal Jr - Cell Death Discovery, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe lower
airway disease and death in a subset of patients. Knowledge on the relative contribution of …

SARS-CoV-2 induces “cytokine storm” hyperinflammatory responses in RA patients through pyroptosis

Q Zheng, R Lin, Y Chen, Q Lv, J Zhang, J Zhai… - Frontiers in …, 2022 - frontiersin.org
Background The coronavirus disease (COVID-19) is a pandemic disease that threatens
worldwide public health, and rheumatoid arthritis (RA) is the most common autoimmune …

Cell deaths: Involvement in the pathogenesis and intervention therapy of COVID-19

X Li, Z Zhang, Z Wang… - Signal transduction and …, 2022 - nature.com
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has dramatically influenced …

The role of cell death in SARS-CoV-2 infection

C Yuan, Z Ma, J Xie, W Li, L Su, G Zhang, J Xu… - Signal transduction and …, 2023 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), showing high
infectiousness, resulted in an ongoing pandemic termed coronavirus disease 2019 (COVID …