Severe cases of COVID-19 are characterized by a strong inflammatory process that may
ultimately lead to organ failure and patient death. The NLRP3 inflammasome is a molecular …

An outbreak of coronavirus disease 2019 (COVID-19) emerged in China in December 2019
and spread so rapidly all around the globe. It's continued and spreading more dangerously …

Pyroptosis is a programmed cell death mode discovered in recent years. It is caused by
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …

The innate immune system serves as the first line of defense against invading pathogens;
however, dysregulated innate immune responses can induce aberrant inflammation that is …

The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …

The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

COVID-19 is spreading and ravaging all over the world, and the number of deaths is
increasing day by day without downward trend. However, there is limited knowledge of …

Pyroptotic cell death or pyroptosis is characterized by caspase-1-dependent formation of
plasma membrane pores, leading to the release of pro-inflammatory cytokines and cell lysis …

Acute respiratory distress syndrome (ARDS) with COVID-19 is aggravated by
hyperinflammatory responses even after the peak of the viral load has passed; however, its …

Pyroptosis is a relatively newly discovered programmed cell death accompanied by an
inflammatory response. In the classical view, pyroptosis is mediated by caspases-1,-4,-5,-11 …