Exploring the role of immune system and inflammatory cytokines in SARS-CoV-2 induced lung disease: a narrative review

C Tirelli, M De Amici, C Albrici, S Mira, G Nalesso, B Re… - Biology, 2023 - mdpi.com
Simple Summary Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the pandemic coronavirus disease-2019 (COVID-19), which can lead to …

Multisystem inflammatory syndrome and autoimmune diseases following COVID-19: molecular mechanisms and therapeutic opportunities

P Hosseini, MS Fallahi, G Erabi, M Pakdin… - Frontiers in molecular …, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), has led to huge concern worldwide. Some SARS-CoV-2 …

Immunology, immunopathogenesis and immunotherapeutics of COVID-19; an overview

LM Khosroshahi, M Rokni, T Mokhtari… - International …, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) infection which is caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to a “public health emergency of …

Is severe COVID-19 a cytokine storm syndrome: a hyperinflammatory debate

P Mehta, DC Fajgenbaum - Current opinion in Rheumatology, 2021 - journals.lww.com
Hyperinflammation is a key component of severe COVID-19, residing underneath the
cytokine storm umbrella term, associated with poor outcomes. Better understanding of the …

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

Tackling the cytokine storm in COVID-19, challenges and hopes

SM Abdin, SM Elgendy, SK Alyammahi, DW Alhamad… - Life Sciences, 2020 - Elsevier
The outbreak of Coronavirus disease 2019 (COVID-19) is the current world health concern,
presenting a public health dilemma with ascending morbidity and mortality rates exceeding …

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

Y Zhou, B Fu, X Zheng, D Wang, C Zhao… - National Science …, 2020 - academic.oup.com
Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV
(SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …

[HTML][HTML] COVID-19 a triggering factor of autoimmune and multi-inflammatory diseases

EK Sher, A Ćosović, A Džidić-Krivić, EK Farhat, E Pinjić… - Life sciences, 2023 - Elsevier
SARS-Cov-2 virus has attracted a lot of attention globally, due to the autoimmune and
inflammatory processes that were observed during the development of Covid-19 disease …

The immune response and immunopathology of COVID-19

E Mortaz, P Tabarsi, M Varahram, G Folkerts… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses were first discovered in the 1960s and are named due to their crown-like
shape. Sometimes, but not often, a coronavirus can infect both animals and humans. An …

Dysregulated innate and adaptive immune responses discriminate disease severity in COVID-19

NAF Janssen, I Grondman… - The Journal of …, 2021 - academic.oup.com
The clinical spectrum of COVID-19 varies and the differences in host response
characterizing this variation have not been fully elucidated. COVID-19 disease severity …