Blood–brain barrier dysfunction in status epileptics: Mechanisms and role in epileptogenesis

E Swissa, Y Serlin, U Vazana, O Prager, A Friedman - Epilepsy & Behavior, 2019 - Elsevier
… epilepticus, and in epileptogenic brain regions, may last for months. Blood–brain barrier
dysfunction was shown to have a role in astroglial dysfunction, neuroinflammation, increasing …

Role of blood-brain barrier dysfunction in epileptogenesis

B INSULTS - Jasper's basic mechanisms of the epilepsies, 2012 - books.google.com
… communication in epileptogenesis, 20 supported by the … for the involvement of BBB dysfunction
in epileptogenesis has … , BBB dysfunction does not seem to induce epileptogenesis by …

Mechanisms underlying blood–brain barrier dysfunction in brain pathology and epileptogenesis: role of astroglia

R Kovács, U Heinemann, C Steinhäuser - Epilepsia, 2012 - Wiley Online Library
… bloodâ•fibrain barrier dysfunction in brain pathology and epileptogenesis: Role of astroglia
… function might critically contribute to epileptogenesis. Therefore, astrocytes represent a …

Blood–brain barrier dysfunction–induced inflammatory signaling in brain pathology and epileptogenesis

SY Kim, M Buckwalter, H Soreq, A Vezzani… - Epilepsia, 2012 - Wiley Online Library
… In this review we examine the role of BBB and inflammatory responses, in particular
activation of transforming grown factor b (TGFb) signaling, in epilepsy, stroke, and Parkinson’s …

Blood‐brain barrier dysfunction in epileptogenesis of the temporal lobe

I Weissberg, A Reichert, U Heinemann… - Epilepsy research …, 2011 - Wiley Online Library
… The frequent findings of BBB dysfunction after brain insults … for a direct role of BBB dysfunction
in epileptogenesis [33]. … for the involvement of BBB dysfunction in epileptogenesis was …

Structural, molecular, and functional alterations of the blood-brain barrier during epileptogenesis and epilepsy: a cause, consequence, or both?

W Löscher, A Friedman - International journal of molecular sciences, 2020 - mdpi.com
… The blood–brain barrier (BBB) is a dynamic and complex barrier essential for the normal
function of the central nervous system (CNS). The existence of a physical interface between the …

Blood–brain barrier dysfunction and epilepsy: pathophysiologic role and therapeutic approaches

N Marchi, T Granata, C Ghosh, D Janigro - Epilepsia, 2012 - Wiley Online Library
… In conclusion, human studies suggestive of a role of BBB dysfunction in seizure disorders are
… These findings are in agreement with a role of BBB damage in epileptogenesis and in the …

Blood‐brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy

UWE Heinemann, D Kaufer, A Friedman - Glia, 2012 - Wiley Online Library
dysfunctional blood-brain barrier (BBB) might underlie such a shift in reorganizational
balance towards epileptogenesis … , point to a potential role of glia in epileptogenesis. It is thus …

Role of blood–brain barrier in temporal lobe epilepsy and pharmacoresistance

EA Van Vliet, E Aronica, JA Gorter - Neuroscience, 2014 - Elsevier
… In the following paragraphs we will discuss changes of these specific functions in relation
to seizures, epileptogenesis and epilepsy. Dysfunction of the physical barrier Adjacent brain

Role of blood–brain barrier dysfunction in the development of poststroke epilepsy

WC Meijer, JA Gorter - Epilepsia, 2024 - Wiley Online Library
… hemorrhagic strokes induce dysfunction of the blood–brain barrier (BBB), and that this
impairment can contribute to epileptogenesis. Nevertheless, studies directly comparing BBB dys…