Immunodominant SARS coronavirus epitopes in humans elicited both enhancing and neutralizing effects on infection in non-human primates

Q Wang, L Zhang, K Kuwahara, L Li, Z Liu… - ACS infectious …, 2016 - ACS Publications
… ) of SARS-CoV infection in vitro and in non-human primatesSARS patients, we identified
and characterized SARS-CoV B-… prevented infection in non-human primates. In contrast, …

The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates

D Li, RJ Edwards, K Manne, DR Martinez, A Schäfer… - BioRxiv, 2021 - biorxiv.org
… HA, and MGL led and performed the non-human primate studies. RSB supervised the
SARS-CoV-1 and bat CoV neutralization assays and the mouse challenge studies. KOS and BFH …

LY-CoV555, a rapidly isolated potent neutralizing antibody, provides protection in a non-human primate model of SARS-CoV-2 infection

BE Jones, PL Brown-Augsburger, KS Corbett… - BioRxiv, 2020 - biorxiv.org
… antibodies (mAbs) to prevent SARS-CoV-2 infection in vivo, … exposure to SARS-CoV-2
or administration of a SARS-CoV-2 … ) Protecting non-human primates (NHPs) from SARS-CoV-2 …

[HTML][HTML] Nonhuman primate models for SARS-CoV-2 research: Consider alternatives to macaques

MC Chang, S Hild, F Grieder - Lab Animal, 2021 - nature.com
… , Zika virus and, most recently, SARS-CoV-2 infection/COVID-19. Nonhuman primates also
have … testing of the SARS-CoV-2 vaccines that will be vital to ending the COVID-19 pandemic. …

[HTML][HTML] Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: A nonhuman primate model of COVID-19 progression

H Zheng, H Li, L Guo, Y Liang, J Li, X Wang… - PLoS …, 2020 - journals.plos.org
SARS-CoV-2 in humans, an effective SARS-CoV-2 infection animal model is urgently needed.
To date, nonhuman primates… models in studies investigating SARS-CoV-2 infection[19, 22]…

[HTML][HTML] Comparison of nonhuman primates identified the suitable model for COVID-19

S Lu, Y Zhao, W Yu, Y Yang, J Gao, J Wang… - Signal transduction and …, 2020 - nature.com
… More specifically, to determine the pathological responses to SARS-CoV-2 infection, we
necropsied eight animals at the early and late stages of infection according to viral load and …

[HTML][HTML] Evaluation of the mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates

KS Corbett, B Flynn, KE Foulds… - … England Journal of …, 2020 - Mass Medical Soc
… Recent studies have shown that SARS-CoV-2 targets similar replication sites and … –like
disease in nonhuman primates. After SARS-CoV-2 infection, nonhuman primates have transient …

[HTML][HTML] Comparison of the immunogenicity & protective efficacy of various SARS-CoV-2 vaccine candidates in non-human primates

L Mukhopadhyay, PD Yadav, N Gupta… - Indian Journal of …, 2021 - journals.lww.com
… The literature on SARS-CoV-2 vaccine studies in NHP models reported on PubMed and
pre-… : coronavirus vaccine, COVID-19 vaccine, SARS-CoV-2vaccine, nonhuman primate and …

Immunization with RBD-P2 and N protects against SARS-CoV-2 in nonhuman primates

SH Hong, H Oh, YW Park, HW Kwak, EY Oh… - Science …, 2021 - science.org
… Since the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), …
in rodents and nonhuman primates (NHPs). We also investigated whether the SARS-CoV-2 …

[HTML][HTML] Antiviral efficacy of favipiravir against Zika and SARS-CoV-2 viruses in non-human primates

R Marlin, D Desjardins, V Contreras, G Lingas… - Nature …, 2022 - nature.com
… against Zika or SARS-CoV-2 virus in cynomolgus macaques. In both … activity against Zika
virus but not against SARS-CoV-2 … virus but they advocate against its use against SARS-CoV-2 …